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Guarana extract
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[[File:Guarana-energy-supplement.jpg|alt=Guarana herbal supplement bottle |thumb]] '''Guarana''' extract or '''guarana seeds''' or '''paullinia cupana''' is a natural [[stimulant]] commonly sold over-the-counter.<ref name="drugscom" /><ref name="Burkey2005">{{Cite web | url=http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.550.343&rep=rep1&type=pdf#page=9 | title = The Use and Abuse of Diet Pills | last = Burkey | first = Heidi | authorlink= | date = 2005 | website = |archive-url=|archive-date=|url-status=|access-date=2020-09-24|journal=Journal of the Health Resource Center|volume=9}}</ref> Guarana seeds are also known as '''Brazilian cocoa''' or '''zoom'''.<ref name="Woods2012">{{Cite journal | last = Woods | first = David J. | date = 2012-06-01 | title = Guarana: Paullinia cupana, P. sorbilis; also known as Brazilian cocoa and 'zoom'| url = https://pubmed.ncbi.nlm.nih.gov/22675703/|journal=Journal of Primary Health Care|volume=4|issue=2 | pages = 163β164|issn=1172-6156|pmid=22675703}}</ref> It is often sold as an "energy supplement" or as in ingredient in "energy drinks" or diet pills.<ref name="Burkey2005" /><ref>{{Cite journal | last = Clauson | first = Kevin A. | last2 = Shields | first2 = Kelly M. | last3 = McQueen | first3 = Cydney E. | last4 = Persad | first4 = Nikki | date = 2008-05-01 | title = Safety issues associated with commercially available energy drinks| url = http://www.sciencedirect.com/science/article/pii/S1544319115312097|journal=Journal of the American Pharmacists Association|language=en|volume=48|issue=3| pages = e55βe67|doi=10.1331/JAPhA.2008.07055|issn=1544-3191}}</ref> ==Purpose == ==Caffeine == Guarana contains [[caffeine]], and guarana supplements often contain other active substances, especially additional [[caffeine]].<ref name="drugscom" /><ref name="Woods2012" /> ==Side effects == Guarana is considered possibly safe if taken in small amounts, but can trigger an allergic reaction in some people. It may interact with other herbs, supplements or medication, including those that also affect blood clotting, e.g. [[garlic|garlic/clove]], ginkgo, [[green tea]], red clover, [[Siberian ginseng]] and [[turmeric]].<ref name="drugscom" /> Some of these are found combined with guarana in herbal supplements or energy drinks.<ref name="Burkey2005" /> The most common side effects include: *[[Diarrhea]] *[[Tachycardia|increased heart rate]] *Increased blood pressure *[[Insomnia]] *Nervousness *Stomach irrational, [[nausea]], or [[vomiting]]<ref name="drugscom" /> *Agitation<ref name="Burkey2005" /> ==Evidence == ==ME/CFS == Guarana has not be proven to be effective for [[chronic fatigue syndrome]].<ref name="drugscom">{{Cite web | url=https://www.drugs.com/mtm/guarana.html | title = Guarana Uses, Side Effects & Warnings|website=Drugs.com|language=en|access-date=2020-09-24}}</ref> There are no clinical trials to show its effectiveness or safety in people with CFS. ==Learn more== *[https://www.drugs.com/mtm/guarana.html Guarana] - drugs.com *The Use and Abuse of Diet Pills - ==See also == *[[Caffeine]] ==References == {{Reflist}} [[Category:Potential treatments]] [[Category:Supplements]] [[Category:Herbs]]
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