Gerwyn Morris

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Gerwyn Morris is an independent researcher with expertise in Microbiology, Cell Biology, and Immunology.[1] He is affiliated with IMPACT Strategic Research Centre, School of Medicine, Deakin University, Barwon Health, Geelong, Victoria, Australia.[2]

Notable studies[edit | edit source]

  • 2013, A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior[3] - (Full text)
  • 2013, In myalgic encephalomyelitis/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation[4] - (Abstract)
  • 2013, Case definitions and diagnostic criteria for Myalgic Encephalomyelitis and Chronic fatigue Syndrome: from clinical-consensus to evidence-based case definitions[5] - (Full text)
  • 2013, Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics[6] - (Abstract)
  • 2014, The emerging role of autoimmunity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/cfs)[7] - (Full text)
  • 2014, Review Article - Mitochondrial dysfunctions in Myalgic Encephalomyelitis/chronic fatigue syndrome explained by activated immuno-inflammatory, oxidative and nitrosative stress pathways[8] - (Abstract)
  • 2014, Oxidative and Nitrosative Stress and Immune-Inflammatory Pathways in Patients with Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS)[9] - (Full Text)
  • 2015, Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses[10] - (Full Text)
  • 2016, The Role of the Microbial Metabolites Including Tryptophan Catabolites and Short Chain Fatty Acids in the Pathophysiology of Immune-Inflammatory and Neuroimmune Disease[11] - (Abstract)
  • 2016, The Many Neuroprogressive Actions of Tryptophan Catabolites (TRYCATs) that may be Associated with the Pathophysiology of Neuro-Immune Disorders[12] - (Abstract)
  • 2016, The deleterious effects of oxidative and nitrosative stress on palmitoylation, membrane lipid rafts and lipid-based cellular signalling: new drug targets in neuroimmune disorders[13] - (Full text)
  • 2016, The Putative Role of Viruses, Bacteria, and Chronic Fungal Biotoxin Exposure in the Genesis of Intractable Fatigue Accompanied by Cognitive and Physical Disability[14] - (Abstract)
  • 2016, The Neuro-Immune Pathophysiology of Central and Peripheral Fatigue in Systemic Immune-Inflammatory and Neuro-Immune Diseases[15] (Abstract)
  • 2016, Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome[16] - (Abstract)
  • 2016, The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimmune processes with an emphasis on Inflammatory Bowel Disease Type 1 Diabetes and Chronic Fatigue Syndrome[17] - (Abstract)
  • 2017, Hypothalamic-Pituitary-Adrenal Hypofunction in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) as a Consequence of Activated Immune-Inflammatory and Oxidative and Nitrosative Pathways[18] - (Abstract)
  • 2017, A Comparison of Neuroimaging Abnormalities in Multiple Sclerosis, Major Depression and Chronic Fatigue Syndrome (Myalgic Encephalomyelitis): is There a Common Cause?[19] - (Full Text)
  • 2017, Mechanisms Explaining Muscle Fatigue and Muscle Pain in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a Review of Recent Findings[20] - (Full Text)
  • 2018, The putative role of oxidative stress and inflammation in the pathophysiology of sleep dysfunction across neuropsychiatric disorders: Focus on chronic fatigue syndrome, bipolar disorder and multiple sclerosis[21] - (Abstract)
  • 2019, The compensatory antioxidant response system with a focus on neuroprogressive disorders[22] - (Abstract)
  • 2019, Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders[23] - (Abstract)
  • 2019, Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?[24] - (Full text)
  • 2019, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: From Pathophysiological Insights to Novel Therapeutic Opportunities[2] - (Abstract)
  • 2019, Editorial - Is a diagnostic blood test for chronic fatigue syndrome on the horizon?[25] - (Full text)
  • 2021, The lipid paradox in neuroprogressive disorders: Causes and consequences[26] - (Full text)
  • 2021, Intertwined associations between oxidative and nitrosative stress and endocannabinoid system pathways: Relevance for neuropsychiatric disorders[27] - (Abstract)

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. "Gerwyn Morris | Independent Researcher". ResearchGate. Retrieved September 23, 2019.
  2. 2.0 2.1 Morris, Gerwyn; Puri, Basant K.; Walker, Adam J.; Maes, Michael; Carvalho, Andre F.; Walder, Ken; Mazza, Catherine; Berk, Michael (September 2019). "Myalgic encephalomyelitis/chronic fatigue syndrome: From pathophysiological insights to novel therapeutic opportunities". Pharmacological Research. 148: 104450. doi:10.1016/j.phrs.2019.104450. PMID 31509764.
  3. Morris, Gerwyn; Anderson, George; Galecki, Piotr; Berk, Michael; Maes, Michael (March 8, 2013). "A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior". BMC Medicine. 11 (1): 64. doi:10.1186/1741-7015-11-64. ISSN 1741-7015. PMC 3751187. PMID 23497361.
  4. Maes, Michael; Ringel, Karl; Kubera, Marta; Anderson, George; Morris, Gerwyn; Galacki, Piotr; Geffard, Michel (September 5, 2013). "In myalgic encephalomyelitis/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation". Journal of Affective Disorders. 150 (2): 223-230. doi:10.1016/j.jad.2013.03.029.
  5. Morris, Gerwyn; Maes, Michael (2013). "Case definitions and diagnostic criteria for Myalgic Encephalomyelitis and Chronic fatigue Syndrome: from clinical-consensus to evidence-based case definitions". Neuro Endocrinology Letters. 34 (3): 185-99. PMID 23685416.
  6. Morris, Gerwyn; Maes, Michael (2013). "Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics". BMC Medicine. 11: 205. doi:10.1186/1741-7015-11-205. ISSN 1741-7015.
  7. Morris, Gerwyn; Berk, Michael; Galacki, Piotr; Maes, Michael (2014). "The emerging role of autoimmunity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/cfs)". Molecular Neurobiology. 49 (2): 741-756. doi:10.1007/s12035-013-8553-0. PMID 24068616.
  8. Morris, Gerwyn; Maes, Michael (2014). "Mitochondrial dysfunctions in Myalgic Encephalomyelitis / chronic fatigue syndrome explained by activated immuno-inflammatory, oxidative and nitrosative stress pathways". Metabolic Brain Disease. 29 (19). doi:10.1007/s11011-013-9435-x.
  9. Morris, Gerwyn; Maes, Michael (2014). "Oxidative and Nitrosative Stress and Immune-Inflammatory Pathways in Patients with Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS)". Current Neuropharmacology. 12 (2): 168–185. doi:10.2174/1570159X11666131120224653. PMC 3964747.
  10. Morris, Gerwyn; Berk, Michael; Walder, K; Maes, Michael (2015). "Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses". BMC Medicine. 13 (28). doi:10.1186/s12916-014-0259-2.
  11. Morris, Gerwyn; Berk, Michael; Carvalho, Andre; Caso, Javier R.; Sanz, Yolanda; Walder, Ken; Maes, Michael; Michael Maes (August 1, 2017). "The Role of the Microbial Metabolites Including Tryptophan Catabolites and Short Chain Fatty Acids in the Pathophysiology of Immune-Inflammatory and Neuroimmune Disease". Molecular Neurobiology. 54 (6): 4432–4451. doi:10.1007/s12035-016-0004-2. ISSN 1559-1182.
  12. Morris, Gerwyn; Carvalho, André F.; Anderson, George; Galecki, Piotr; Maes, Michael (2016). "The Many Neuroprogressive Actions of Tryptophan Catabolites (TRYCATs) that may be Associated with the Pathophysiology of Neuro-Immune Disorders". Current Pharmaceutical Design. 22 (8): 963–977. doi:10.2174/1381612822666151215102420. ISSN 1873-4286. PMID 26667000.
  13. Morris, Gerwyn; Walder, Ken; Puri, Basant K.; Berk, Michael; Maes, Michael (September 1, 2016). "The Deleterious Effects of Oxidative and Nitrosative Stress on Palmitoylation, Membrane Lipid Rafts and Lipid-Based Cellular Signalling: New Drug Targets in Neuroimmune Disorders". Molecular Neurobiology. 53 (7): 4638–4658. doi:10.1007/s12035-015-9392-y. ISSN 1559-1182.
  14. Morris, Gerwyn; Berk, Michael; Walder, Ken; Maes, Michael (May 2016). "The Putative Role of Viruses, Bacteria, and Chronic Fungal Biotoxin Exposure in the Genesis of Intractable Fatigue Accompanied by Cognitive and Physical Disability". Molecular Neurobiology. 53 (4): 2550–2571. doi:10.1007/s12035-015-9262-7. ISSN 1559-1182. PMID 26081141.
  15. Morris, Gerwyn; Berk, Michael; Galecki, Piotr; Walder, Ken; Maes, Michael (March 2016). "The Neuro-Immune Pathophysiology of Central and Peripheral Fatigue in Systemic Immune-Inflammatory and Neuro-Immune Diseases". Molecular Neurobiology. 53 (2): 1195–1219. doi:10.1007/s12035-015-9090-9. ISSN 1559-1182. PMID 25598355.
  16. Morris, Gerwyn; Berk, Michael; Klein, H.; Walder, K.; Galacki, Piotr; Maes, Michael (June 23, 2016). "Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome". Molecular Neurobiology. 54: 4271–4291. doi:10.1007/s12035-016-9975-2.
  17. Morris, Gerwyn; Berk, Michael; Carvalho, A.F.; Caso, J.R.; Sanz, Y.; Maes, Michael (2016). "The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimmune processes with an emphasis on Inflammatory Bowel Disease Type 1 Diabetes and Chronic Fatigue Syndrome". Current Pharmaceutical Design. 22 (40): 6058-6075. PMID 27634186.
  18. Morris, Gerwyn; Anderson, George; Maes, Michael (November 2017). "Hypothalamic-Pituitary-Adrenal Hypofunction in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) as a Consequence of Activated Immune-Inflammatory and Oxidative and Nitrosative Pathways". Molecular Neurobiology. 54 (9): 6806–6819. doi:10.1007/s12035-016-0170-2. ISSN 1559-1182. PMID 27766535.
  19. Morris, Gerwyn; Berk, Michael; Puri, Basant K. (2017). "A Comparison of Neuroimaging Abnormalities in Multiple Sclerosis, Major Depression and Chronic Fatigue Syndrome (Myalgic Encephalomyelitis): is There a Common Cause?". Mol Neurobiology. 55 (4): 3592–3609. doi:10.1007/s12035-017-0598-z.
  20. Morris, Gerwyn; Maes, Michael (2017). "Mechanisms Explaining Muscle Fatigue and Muscle Pain in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a Review of Recent Findings". Current Rheumatology Reports. 19 (1). doi:10.1007/s11926-017-0628-x.
  21. Morris, Gerwyn; Stubbs, Brendon; Köhler, Cristiano A.; Walder, Ken; Slyepchenko, Anastasiya; Berk, Michael; Carvalho, André F. (2018). "The putative role of Oxidative Stress and Inflammation in the pathophysiology of sleep dysfunction across neuropsychiatric disorders : Focus on Chronic Fatigue Syndrome, Bipolar Disorder and Multiple Sclerosis". Sleep Med Reviews. 41: 255–265. doi:10.1016/j.smrv.2018.03.007. PMID 29759891.
  22. Morris, Gerwyn; Puri, Basant K.; Walker, Adam J.; Berk, Michael; Walder, Ken; Bortolasci, Chiara C.; Marx, Wolfgang; Carvalho, Andre F.; Maes, Michael (December 20, 2019). "The compensatory antioxidant response system with a focus on neuroprogressive disorders". Progress in Neuro-Psychopharmacology and Biological Psychiatry. 95: 109708. doi:10.1016/j.pnpbp.2019.109708. ISSN 0278-5846.
  23. Morris, Gerwyn; Puri, Basant K.; Walker, Adam J.; Maes, Michael; Carvalho, Andre F.; Bortolasci, Chiara C.; Walder, Ken; Berk, Michael (December 1, 2019). "Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders". Neuroscience & Biobehavioral Reviews. 107: 862–882. doi:10.1016/j.neubiorev.2019.09.025. ISSN 0149-7634.
  24. Morris, Gerwyn; Maes, Michael; Berk, Michael; Puri, Basant K. (February 13, 2019). "Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?". Metabolic Brain Disease. doi:10.1007/s11011-019-0388-6. ISSN 0885-7490. PMID 30758706.
  25. Maes, Michael; Rodriguez, Laura Andres; Morris, Gerwyn (October 18, 2019). "Is a diagnostic blood test for chronic fatigue syndrome on the horizon?". Expert Review of Molecular Diagnostics. 19 (12): 1049–1051. doi:10.1080/14737159.2020.1681976. ISSN 1473-7159.
  26. Morris, Gerwyn; Berk, Michael; Walder, Ken; O'Neil, Adrienne; Maes, Michael; Puri, Basant K. (September 1, 2021). "The lipid paradox in neuroprogressive disorders: Causes and consequences". Neuroscience & Biobehavioral Reviews. 128: 35–57. doi:10.1016/j.neubiorev.2021.06.017. ISSN 0149-7634.
  27. Morris, Gerwyn; Walder, Ken; Berk, Michael; Carvalho, Andre F.; Marx, Wolf; Bortolasci, Chiara C.; Yung, Alison R.; Puri, Basant K.; Maes, Michael (November 24, 2021). "Intertwined associations between oxidative and nitrosative stress and endocannabinoid system pathways: Relevance for neuropsychiatric disorders". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 114: 110481. doi:10.1016/j.pnpbp.2021.110481. ISSN 1878-4216. PMID 34826557.