Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
GABA
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
{{Cleanup/Citations needed | date = Dec 2019|reason=No references}} '''Gamma aminobutyric acid''' (GABA), is a [[neurotransmitter]] made from the [[:Category:Amino acids|amino acid]] [[glutamate]]. GABA is the chief inhibiting, or calming [[neurotransmitter]] in the [[brain]], functioning as a brake on the neural circuitry during [[stress]]. Low GABA levels are associated with [[restlessness]], [[anxiety]], [[insomnia]] and a low mood/[[depression]]. GABA works to balance [[glutamate]] (excitatory) in the brain. GABA is the brake pedal on a car while glutamate is the gas pedal.{{citation needed}} Supplements to support GABA and glutamate are: *amino acids GABA *[[theanine|L-theanine]] *[[N-acetyl-cysteine]] (NAC) *[[vitamin B6]] *[[vitamin D]] *[[magnesium]] *[[zinc]] *[[Omega 3 fatty acid]], and *[[inositol]]{{citation needed | date = September 2020}} ==Notable studies== *2005, [https://www.ncbi.nlm.nih.gov/pubmed/15757488 GABA and glutamate systems as therapeutic targets in depression and mood disorders]<ref>{{Cite journal | last = Kendell | first = Steven F. | author-link = | last2 = Krystal | first2 = John H. | authorlink2 = | last3 = Sanacora | first3 = Gerrard | authorlink3 = | date = February 2005 | title = GABA and glutamate systems as therapeutic targets in depression and mood disorders| url = https://www.ncbi.nlm.nih.gov/pubmed/15757488|journal=Expert Opinion on Therapeutic Targets|volume=9|issue=1| pages=153β168|doi=10.1517/14728222.9.1.153|issn=1744-7631|pmc=|pmid=15757488|access-date=|quote=|via=}}</ref> *2005, [https://www.ncbi.nlm.nih.gov/pubmed/16400244 Beyond monoamines: glutamatergic function in mood disorders]<ref>{{Cite journal | last = Kugaya | first = Akira | author-link = | last2 = Sanacora | first2 = Gerard | authorlink2 = | date = Oct 2005 | title = Beyond monoamines: glutamatergic function in mood disorders| url = https://www.ncbi.nlm.nih.gov/pubmed/16400244|journal=CNS spectrums|volume=10|issue=10 | pages = 808β819|doi=10.1017/s1092852900010403|issn=1092-8529|pmc=|pmid=16400244|access-date=|quote=|via=}}</ref> *2006, [https://www.ncbi.nlm.nih.gov/pubmed/16971751 Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans]<ref name="pmid16971751">{{Cite journal | last = Abdou | first = Adham M. | last2 = Higashiguchi | first2 = S. | last3 = Horie | first3 = K. | last4 = Kim | first4 = Mujo | last5 = Hatta | first5 = H. | last6 = Yokogoshi | first6 = H. | date = 2006 | title=Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans| url = https://pubmed.ncbi.nlm.nih.gov/16971751/|journal=BioFactors (Oxford, England)|volume=26|issue=3 | pages = 201β208|doi=10.1002/biof.5520260305|issn=0951-6433|pmid=16971751}}</ref> *2007, Thorne Research, Inc: Gamma-Aminobutyric Acid (GABA). Alternative Medicine Review, 2007; 12(3) ==See also== *[[Glutamate]] *[[:Category:Neurotransmitters|Neurotransmitters (category)]] ==Learn more == ==References== {{Reflist}} [[Category:Neurotransmitters]] [[Category:Amino acids]] [[Category:Depression alternative treatments]] [[Category:Depression treatments]]
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Templates used on this page:
Template:Ambox
(
edit
)
Template:Category handler
(
edit
)
Template:Citation needed
(
edit
)
Template:Cite journal
(
edit
)
Template:Cleanup
(
edit
)
Template:Cleanup/Citations needed
(
edit
)
Template:Cleanup reason text
(
edit
)
Template:Colon
(
edit
)
Template:DMC
(
edit
)
Template:DMCA
(
edit
)
Template:Dated maintenance category
(
edit
)
Template:Digits
(
edit
)
Template:FULLROOTPAGENAME
(
edit
)
Template:Fix
(
edit
)
Template:Fix/category
(
view source
) (protected)
Template:Full stop
(
edit
)
Template:Full stop character
(
edit
)
Template:GetFallback
(
edit
)
Template:Help improve text
(
edit
)
Template:LangSwitch
(
edit
)
Template:Last word
(
edit
)
Template:Main other
(
edit
)
Template:No fullstop
(
edit
)
Template:No fullstop/first
(
edit
)
Template:Ns has subpages
(
edit
)
Template:Reflist
(
edit
)
Template:Str endswith
(
edit
)
Template:Str len
(
edit
)
Template:Uselang
(
edit
)
Template:Year
(
edit
)
Module:Arguments
(
edit
)
Module:Category handler
(
edit
)
Module:Category handler/blacklist
(
edit
)
Module:Category handler/config
(
edit
)
Module:Category handler/data
(
edit
)
Module:Category handler/shared
(
edit
)
Module:Check for unknown parameters
(
edit
)
Module:Citation/CS1
(
edit
)
Module:Citation/CS1/COinS
(
edit
)
Module:Citation/CS1/Configuration
(
edit
)
Module:Citation/CS1/Date validation
(
edit
)
Module:Citation/CS1/Identifiers
(
edit
)
Module:Citation/CS1/Utilities
(
edit
)
Module:Citation/CS1/Whitelist
(
edit
)
Module:Message box/configuration
(
edit
)
Module:Message box by year
(
edit
)
Module:Namespace detect/config
(
edit
)
Module:Namespace detect/data
(
edit
)
Module:No globals
(
edit
)
Module:Ns has subpages
(
edit
)
Module:String
(
edit
)
Module:Unsubst
(
edit
)
Module:Yesno
(
edit
)
This page is a member of 6 hidden categories:
Category:All articles needing cleanup from 2019
Category:All articles with unsourced statements
Category:Articles needing many references adding from 2019
Category:Articles with unsourced statements from 2020
Category:Articles with unsourced statements from unknown year
Category:Cleanup tagged articles with a reason field from 2019
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs