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Fatigue reduction diet
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==Evidence== The FRD was originally tested with a 3 month pilot study of just 15 fatigued breast cancer survivors, with an average age of early 60s, all of which had low fruit and vegetable intake, and none of which had fatigue caused by [[ME/CFS]] or other illness.<ref name="Zick2016" /><ref name="pres">{{Cite web | url = https://medicine.umich.edu/sites/default/files/content/downloads/Suzanna%20Zick-%20Friday%20Afternoon%20-%20Using%20Diet%20to%20Combat%20Persistent%20Fatigue%20in%20Cancer.pdf | access-date=2021-12-28 | website = Department of Family Medicine UMHS | title = Fatigue Reduction Diet in Breast Cancer Survivors: A Pilot Randomized Clinical Trial | last = Zich | first = Susanna}}</ref> The Fatigue Reduction Diet was compared to a to more general healthy balanced diet and was found to improve sleep and reduce fatigue in the cancer survivors. Blood analysis of cancer survivors on the Fatigue Reduction Diet found that reduction in fatigue was linked to increased [[Eicosapentaenoic acid|EPA]] intake and improved [[Omega 3 fatty acid hypothesis|omega 3 to omega 6 ratio]].<ref name="Zick2016" /> Participants in the pilot study had an average [[Brief Fatigue Inventory]] score of 5.4, such reduced to 3 after 3 months on the Fatigue Reduction Diet.<ref name="Zick2016" /> There are no studies on the effects of the FRD on patients with [[ME/CFS]].
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