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Famotidine
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'''Famotidine''' is a non-sedating antihistamine that blocks the H2 histamine receptor. Famotidine is available over the counter and on perscription and is used to treat and prevent ulcers, [[gastroesophageal reflux disease]] (GERD) and other conditions that cause [[heartburn]].<ref name="drugscom"/> Famotidine brand names include Pepcid and Zantac 360 (not to be confused with Zantac, which contains different active ingredients).<ref name="drugscom">{{Cite web | url=https://www.drugs.com/famotidine.html | title = Famotidine Uses, Dosage & Side Effects|website=Drugs.com|language=en|access-date=2022-02-19}}</ref><ref name="webmd">{{Cite web | url=https://www.webmd.com/drugs/2/drug-5035-250/famotidine-oral/famotidine-10-mg-oral/details | title = Famotidine - Uses, Side Effects, and More|website=WebMD|language=en|access-date=2022-02-19}}</ref><ref name="drugbank">{{Cite web | url=https://go.drugbank.com/drugs/DB00927 | title = Famotidine: Uses, Interactions, Mechanism of Action|website=Drugbank Online|language=en|access-date=2022-02-19}}</ref> ==Theory== ==Evidence== ===Long COVID === Famotidine has limited evidence for use in [[Long COVID]] patients from a small observational study by Glynne et al. (2022), in which H1 and H2 blockers were used together.<ref name="Glynne2022"/> ==Clinicians== ==Risks and safety== ==Costs and availability== Available over the counter or on perscription.<ref name="drugscom" /><ref name="drugbank"/><ref name="webmd" /> ==Notable studies == *2022, Long COVID following mild SARS-CoV-2 infection: characteristic T cell alterations and response to antihistamines<ref name="Glynne2022">{{Cite journal | title = Long COVID following mild SARS-CoV-2 infection: characteristic T cell alterations and response to antihistamines | date = Jan 2022| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494538/|journal=Journal of Investigative Medicine|volume=70|issue=1 | pages = 61β67 | last = Glynne | first = Paul | authorlink = Paul Glynne | last2 = Tahmasebi | first2 = Natasha | authorlink2 = | last3 = Gant | first3 = Vanya | authorlink3 = | last4 = Gupta | first4 = Rajeev | authorlink4 = |doi=10.1136/jim-2021-002051|pmc=8494538|pmid=34611034|access-date=|issn=1081-5589|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494538/ (Full text)] ==See also == *[[Gastroesophageal reflux disease]] *[[Histamine]] *[[Long COVID]] ==Learn more == *[https://go.drugbank.com/drugs/DB00927 Famotidine] - DrugBank Online *[https://www.drugs.com/famotidine.html Famotidine] - drugs.com *[https://www.webmd.com/drugs/2/drug-5035-250/famotidine-oral/famotidine-10-mg-oral/details Famotidine] - WebMD ==References == {{Reflist}} [[Category:Potential treatments]] [[Category:Antihistamines]] [[Category:H2 antihistamines]]
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