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Epstein-Barr virus
(section)
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=== Systemic lupus erythematosus === In a study of young patients with lupus, 99% had EBV as compared to 70% of healthy controls.<ref name="James1997">{{Cite journal | title = An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. | date = 1997-12-15| url = https://www.jci.org/articles/view/119856|journal=The Journal of Clinical Investigation|volume=100|issue=12 | pages = 3019β3026 | last = James | first = J.A. | last2 = Kaufman | first2 = K.M. | last3 = Farris | first3 = A.D. | last4 = Taylor-Albert | first4 = E. | last5 = Lehman | first5 = T.J. | last6 = Harley | first6 = J.B.|language=en|doi=10.1172/JCI119856|pmid=9399948|issn=0021-9738}}</ref> Another study found that patients with systemic lupus erythematosus had a roughly 40-fold increase in EBV viral loads compared with controls, likely stemming from altered [[t cell]] responses against EBV.<ref>{{Cite journal | title = Defective Control of Latent Epstein-Barr Virus Infection in Systemic Lupus Erythematosus | date = 2004-01-15| url = https://www.jimmunol.org/content/172/2/1287|journal=The Journal of Immunology|volume=172|issue=2 | pages = 1287β1294 | last = Kang | first = Insoo | last2 = Quan | first2 = Timothy | last3 = Nolasco | first3 = Helena | last4 = Park | first4 = Sung-Hwan | last5 = Hong | first5 = Myung Sun | last6 = Crouch | first6 = Jill | last7 = Pamer | first7 = Eric G. | last8 = Howe | first8 = John Greg | last9 = Craft | first9 = Joe|language=en|doi=10.4049/jimmunol.172.2.1287|pmid=14707107|issn=0022-1767}}</ref>
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