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Enterovirus
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== Treatment == There are no [[U.S. Food and Drug Administration|FDA]] approved treatments for enteroviruses. The drug [[Pleconaril]] has been shown to have activity against a number of enteroviruses<ref name="Rotbart2001">{{Citation | last1 = Rotbart | first1 = HA | author-link1 = Harley A Rotbart | last2 = Webster | first2 = AD | authorlink2 = A. David Webster | title = Treatment of Potentially Life-Threatening Enterovirus Infections with Pleconaril| journal = Clinical Infectious Diseases| volume = 32 | issue = 2| pages = 228–235 | date = Jan 15, 2001 | pmid = 11170912 | doi = 10.1086/318452 | url = http://cid.oxfordjournals.org/content/32/2/228}}</ref><ref name="Pevear1999">{{Citation | last1 = Pevear | first1 = Daniel C | last2 = Tull | first2 = Tina M | last3 = Seipel | first3 = Martin E | last4 = Groarke | first4 = James M | title = Activity of Pleconaril against Enteroviruses | journal = Antimicrobial Agents and Chemotherapy | volume = 43 | issue = 9| pages = 2109–2115 | date = Sep 1, 1999 | pmid = 10471549 | url = http://aac.asm.org/content/43/9/2109 }}</ref><ref name="Bauer2002">{{Citation | last1 = Bauer | first1 = Sofia | last2 = Gottesman | first2 = Giora | last3 = Sirota | first3 = Lea | last4 = Litmanovitz | first4 = Ita | last5 = Ashkenazi | first5 = Shay | last6 = Levi | first6 = Itzhak | title = Severe Coxsackie virus B infection in preterm newborns treated with pleconaril | journal = European Journal of Pediatrics | volume = 161 | issue = 9| pages = 491–493 | date = Jul 23, 2002 | doi = 10.1007/s00431-002-0929-5 | url = http://link.springer.com/article/10.1007/s00431-002-0929-5 }}</ref><ref name="Groarke1999">{{Citation | last1 = Groarke | first1 = James M | last2 = Pevear | first2 = Daniel C | title = Attenuated Virulence of Pleconaril-Resistant Coxsackievirus B3 Variants | journal = Journal of Infectious Diseases | volume = 179 | issue = 6| pages = 1538–1541 | date = Jun 1, 1999 | pmid = 10228078 | doi = 10.1086/314758 | url = http://jid.oxfordjournals.org/content/179/6/1538 }}</ref><ref name="Abzug2016">{{Citation | last1 = Abzug | first1 = Mark J | last2 = Michaels | first2 = Marian G | last3 = Wald | first3 = Ellen | last4 = Jacobs | first4 = Richard F | last5 = Romero | first5 = José R | last6 = Sánchez | first6 = Pablo J | last7 = Wilson | first7 = Gregory | last8 = Krogstad | first8 = Paul | last9 =Storch | first9 = Gregory A | last10 = Lawrence | first10 = Robert | last11 = Shelton | first11 = Mark | last12 = Palmer | first12 = April | last13 = Robinson | first13 = Joan | last14 = Dennehy | first14 = Penelope | last15 = Sood | first15 = Sunil K | last16 = Cloud | first16 = Gretchen | last17 = Jester | first17 = Penelope | last18 = Acosta | first18 = Edward P | last19 = Whitley | first19 = Richard | last20 = Kimberlin | first20 = David | last21 = National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group | title = A Randomized, Double-Blind, Placebo-Controlled Trial of Pleconaril for the Treatment of Neonates With Enterovirus Sepsis | journal = Journal of the Pediatric Infectious Diseases Society | volume = 5 | issue = 1| pages = 53–62 | date = Mar 2016 | pmid = 26407253 | doi = 10.1093/jpids/piv015 | url = http://journals.lww.com/pidj/Abstract/2003/04000/Double_blind_placebo_controlled_trial_of.9.aspx}}</ref> but has not been approved by the FDA. Treatment usually involves supporting the [[immune response]] particularly in those with documented [[immune dysfunction]]. Dr. Chia treats his patients with enteroviral infection with [[Equilibrant]], [[gammaglobulin]] and [[interferon]].<ref name="evmed-treatment">{{citation | title = Treatments for Chronic Fatigue Syndrome | type = webpage | journal = EvMed Research | url = http://www.evmedresearch.com/education/treatment.php}}</ref>
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