Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Endometriosis
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
'''Endometriosis''' is an gynacological disease in which the cells and layer of tissue that resembling endometrium (the lining of the uterus) grow outside of it, for example in the ovaries and fallopian tubes. This causes chronic inflammation that can result in scar tissue (adhesions, fibrosis), especially in the pelvis. Endometriosis is a potential co-morbidity of [[chronic fatigue syndrome]].<ref name="WHO-facts">{{Cite web | url = https://www.who.int/news-room/fact-sheets/detail/endometriosis | title = Endometriosis | last =World Health Organization | first = | authorlink = World Health Organization | last2= | first2 = | authorlink2= | date = |website=World Health Organization|language=en|archive-url=|archive-date=|url-status=|access-date=2023-01-19}}</ref><ref name="NHS">{{Cite web | url = https://www.nhs.uk/conditions/endometriosis/ | title = Endometriosis | last = | first = | authorlink = | date = 2017-10-20|website=National Health Service|language=en|archive-url=|archive-date=|url-status=|access-date=2023-01-19}}</ref> Endometriosis can affect teenagers as well as older adults, and is a long term condition. It is estimated to affect around 10% of women (people assigned female at birth), particularly during their reproductive years.<ref name="NHS" /> ===Lesions=== Lesions in endometriosis may occur on the ovaries, recto-vaginal septum, bladder, and bowel. In rare cases, endometriosis has also been found outside the pelvis.<ref name="WHO-facts" /> == Signs and symptoms == Endometriosis symptoms may include: * [[Dysmenorrhea]] * Heavy or irregular bleeding * [[Pelvic pain]] * Lower [[abdominal pain]] or [[lower back pain|back pain]] * Dyspareunia * Dyschezia (pain on defecation) - Often with cycles of [[diarrhea]] and [[constipation]] * [[Bloating]], [[nausea]], and [[vomiting]] * Inguinal pain * Pain during urinartion and/or [[urinary frequency]] * Pain during [[exercise]] * Pain during sex * Fertility problems * [[Depression]] or [[anxiety]]<ref name="WHO-facts" /><ref name="NHS" /><ref name="Medscape">{{Cite web | url=https://emedicine.medscape.com/article/271899-overview?pa=jMRaWR4PAEnCN4KmIE2ERdgxGc7U%2BJXHgafXryaB0qWOHn2h4Vo%2BTCVWAoDQP20qLFCGYpc1SijZgso3xZYs3odHiuSJDifRp%2BEZ0GL%2FEKg%3D | title = Endometriosis | last = Davila | first = G. Willy | date = Dec 5, 2017 | website = Medscape |access-date=}}</ref> One third of women with endometriosis have no symptoms.<ref name="WHO-facts" /><ref name="NHS" /><ref name="Medscape">{{Cite web | url=https://emedicine.medscape.com/article/271899-overview?pa=jMRaWR4PAEnCN4KmIE2ERdgxGc7U%2BJXHgafXryaB0qWOHn2h4Vo%2BTCVWAoDQP20qLFCGYpc1SijZgso3xZYs3odHiuSJDifRp%2BEZ0GL%2FEKg%3D | title = Endometriosis | last = Davila | first = G. Willy | date = Dec 5, 2017 | website = Medscape |access-date=}}</ref> == Co-morbidities == === ME/CFS === Patients with [[ME/CFS]] may have higher rates of [[gynecologic disorders]] including endometriosis, [[ovarian cyst]]s, [[PCIS|polycystic ovaries]], [[uterine fibroids]], [[menstrual]] abnormalities and [[galactorrhea]].<ref>{{Cite journal | last = Harlow | first = BL | date = 28 September 1998 | title = Reproductive correlates of chronic fatigue syndrome | url =https://www.ncbi.nlm.nih.gov/pubmed/9790489|journal=American Journal of Medicine |volume= | pages = |via=}}</ref> A 2018 study by the [[Centers for Disease Control and Prevention]] stated that more than a third of women with CFS (36.1%) reported endometriosis as a comorbid condition. Women with both CFS and endometriosis report more chronic pelvic pain, earlier menopause, hysterectomy, and more CFS-related symptoms compared to women with CFS-only.<ref name="Boneva2018">{{Cite journal | last = Boneva | first = Roumiana S. | authorlink = | last2 = Lin | first2 = Jin-Mann S. | authorlink2 = Jin-Mann Sally Lin | last3 = Wieser | first3 = Friedrich | authorlink3 = | last4 = Nater | first4 = Urs M. | author-link4 = | last5 = Ditzen | first5 = Beate | authorlink5 = | last6 = Taylor | first6 = Robert N. | author-link6 = | last7 = Unger | first7 = Elizabeth R. | author-link7 = Elizabeth Unger | date = Apr 2018 | title = Endometriosis as a Comorbid Condition in Chronic Fatigue Syndrome (CFS): Secondary Analysis of Data from a CFS Case-Control study| url = https://www.frontiersin.org/articles/10.3389/fped.2019.00195/abstract|journal=Frontiers in Pediatrics|volume=|issue= | pages = |doi=10.3389/fped.2019.00195|quote=|via=}}</ref> Sinali et al (2002) also found high rates of chronic fatigue syndrome in endometriosis patients.<ref name="Stein2002" /> === Fibromyalgia === Sinali et al (2002) found people with endometriosis had high rates of fibromyalgia.<ref name="Stein2002" /> == Other comorbidities == Sinali et al (2002) also found people with endometriosis often had autoimmune diseases, endocrine (hormone) diseases, and atopic or allergy-related conditions.<ref name="Stein2002" /> ==Treatments== Treatments include: * Contraceptive steroids * [[Nonsteroidal anti-inflammatory drug]]s * Gonadotropin-releasing hormone (GnRH) agonists, which reduce estrogen llevels * Infertility treatments * Surgery may sometimes be used to remove endometriosis lesions, adhesions, and scar tissue<ref name="GnRH">{{Cite web | url = https://endometriosis.org/treatments/gnrh/ | title = GnRH | last = | first = | authorlink = | last2= | first2 = | authorlink2= | date = |website=Endometriosis.org|language=en|archive-url=|archive-date=|url-status=|access-date=2023-01-20}}</ref> == Research studies == * 2019, Endometriosis as a Comorbid Condition in Chronic Fatigue Syndrome (CFS): Secondary Analysis of Data from a CFS Case-Control study<ref name="Boneva2018" /> *2002, High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome, and atopic diseases among women with endometriosis: A survey analysis<ref name="Stein2002">{{Cite journal | title = High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis| date = Oct 2002 | url = https://pubmed.ncbi.nlm.nih.gov/12351553/|journal=Human Reproduction (Oxford, England)|volume=17|issue=10|pages=2715β2724 | last =Sinaii | first =N. | author-link = | last2=Cleary | first2 = S. D. | author-link2 = | last3=Ballweg | first3 = M. L. | author-link3 = | last4 = Nieman | first4 = L. K. | author-link4 = | last5 = Stratton | first5 = P. | author-link5 = | last9 = | first9 = |doi=10.1093/humrep/17.10.2715|pmc=|pmid=12351553|access-date=|issn=0268-1161|quote=|via=}}</ref> - [http://www.ncbi.nlm.nih.gov/pubmed/12351553 (Abstract)] ==News and articles == * [https://www.newscientist.com/article/2354004-genetic-map-of-cells-linked-to-endometriosis-could-improve-treatments/ Genetic map of cells linked to endometriosis could improve treatments] - New Scientist ==See also == * [[Menstrual problems in ME/CFS]] * [[Chronic pain]] ==Learn more == * [https://www.who.int/news-room/fact-sheets/detail/endometriosis Endometriosis factsheet] - World Health Organization *[https://endometriosis.org/treatments/gnrh/ Gonadotropin-releasing hormone (GnRH) agonists] - Endometriosis.org * [https://www.nhs.uk/conditions/endometriosis/ Endometriosis] - NHS == References == {{reflist}} [[Category:Diagnoses]] [[Category:Potential comorbidities]] [[Category:Genitourinary diseases and disorders]]
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Templates used on this page:
Template:Cite journal
(
edit
)
Template:Cite web
(
edit
)
Template:Main other
(
edit
)
Template:Reflist
(
edit
)
Module:Check for unknown parameters
(
edit
)
Module:Citation/CS1
(
edit
)
Module:Citation/CS1/COinS
(
edit
)
Module:Citation/CS1/Configuration
(
edit
)
Module:Citation/CS1/Date validation
(
edit
)
Module:Citation/CS1/Identifiers
(
edit
)
Module:Citation/CS1/Utilities
(
edit
)
Module:Citation/CS1/Whitelist
(
edit
)
Module:No globals
(
edit
)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs