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[[File:Elisa Oltra.png|thumb|right|Source: www.researchgate.net]]
[[File:Elisa Oltra.png|thumb|right|Source: www.researchgate.net]]
'''Elisa Oltra''', PhD., is a professor of Cell and Molecular Biology at the Universidad Cat&oacute;lica de Valencia "San Vicente M&aacute;rtir", Valencia, Spain.  Her areas of research include stem cell, cancer, fibromyalgia and genetics.<ref>https://www.researchgate.net/profile/Elisa_Oltra</ref><ref>http://www.oei.es/divulgacioncientifica/entrevistas_072.htm</ref>
'''Elisa Oltra''', aka '''Elisa Oltra Garcia''', PhD., is a professor of Cell and Molecular Biology at the Universidad Cat&oacute;lica de Valencia "San Vicente M&aacute;rtir", Valencia, [[Spain]].  Her areas of research include stem cell, cancer, fibromyalgia and genetics.<ref>{{Cite web |  url = https://www.researchgate.net/profile/Elisa_Oltra | title = ELISA OLTRA {{!}} PhD {{!}} Catholic University of Valencia "San Vicente Martir", Valencia {{!}} Biomedicine|website=ResearchGate|language=en|access-date=2020-02-18}}</ref><ref>{{Cite web |  url = https://www.oei.es/historico/divulgacioncientifica/entrevistas_072.htm | title = Elisa Oltra García: “Trabajamos en el desarrollo de un test válido y objetivo para el diagnóstico de la fibromialgia” | website = oei.es|access-date=2019-05-02}}</ref>


==2017 Ramsay Award==
==2017 Ramsay Award==
A team comprised of Dr. Elisa Oltra of Universidad Católica de Valencia, Spain, and Drs. [[Lubov Nathanson]], Vladimir Beljanski and Malav Suchin Trivedi of Nova Southeastern University, USA, were awarded a 2017 Ramsay Award grant from the [[Solve ME/CFS Initiative]] for researching the effect of [[ME/CFS]] on epigenetic regulation in specific immune cell types.<ref>http://solvecfs.org/2017-ramsay-award-program-results/</ref>
A team comprised of Dr. Elisa Oltra of Universidad Católica de Valencia, Spain, and Drs. [[Lubov Nathanson]], Vladimir Beljanski and Malav Suchin Trivedi of Nova Southeastern University, US, were awarded a 2017 [[Ramsay Award]] grant from the [[Solve ME/CFS Initiative]] for researching the effect of [[ME/CFS]] on epigenetic regulation in specific immune cell types.<ref>{{Cite web |  url = https://solvecfs.org/2017-ramsay-award-program-results/ | title = 2017 Ramsay Award Program Results|website=Solve ME/CFS Initiative|language=en-US|access-date=2019-05-02}}</ref>


==ME/CFS Common Data Element (CDE) Project==
== Committees and working groups ==
Chair of the Biomarkers Working Group and a member of the Baseline/Covariate Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the [[National Institute of Neurological Disorders and Stroke]] and the [[Centers for Disease Control & Prevention]].<ref>https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?%2fnindscdereports%2fRoster&rs%3aCommand=Render&rc:Parameters=false&diseaseid=MECFS&custom:disableExcel=true&custom:disableXML=true&custom:disableCSV=true</ref>
 
===ME/CFS Common Data Element (CDE) Project===
Chair of the Biomarkers Working Group and a member of the Baseline/Covariate Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the [[National Institute of Neurological Disorders and Stroke]] and the [[Centers for Disease Control and Prevention]].<ref>{{Cite web |  url = https://www.commondataelements.ninds.nih.gov/Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome#pane-138 | title = Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster | last = | first = | authorlink = | date = | website = NIH| archive-url = | archive-date = |url-status = | access-date=2019-10-11}}</ref>
 
=== EUROMENE ===
Participating member of the [[Biomarkers]] Working Group of [[EUROMENE]], a European Union, COST Action CA15111, not-for-profit research organization committed to tackling the cause and treatment for [[ME/CFS|Myalgic Encephalomyelitis/Chronic Fatigue Syndrome]].<ref>{{Cite web |  url = https://www.cost.eu/actions/CA15111/ | title = Action CA15111 | website = COST|language=en-GB|access-date=2019-07-16}}</ref>


==Notable studies==
==Notable studies==
*2017, The European [[ME/CFS]] [[Biomarker]] Landscape project: an initiative of the European network [[EUROMENE]]<ref name="EUROMENE2017"/> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530475/ (Full Text)]
*2017, The European ME/CFS [[Biomarker]] Landscape project: an initiative of the European network EUROMENE<ref>{{Cite journal | last = Scheibenbogen | first = Carmen  | author-link = Carmen Scheibenbogen | last2 = Freitag | first2 = Helma | authorlink2 = Helma Freitag | last3 = Blanco | first3 = Julià | authorlink3 = Julià Blanco | last4 = Capelli | first4 = Enrica | authorlink4 = Enrica Capelli | last5 = Lacerda | first5 = Eliana | authorlink5 = Eliana Lacerda | last6 = Authier | first6 = Jerome | author-link6 = François Jérôme Authier | last7 = Meeus | first7 = Mira | author-link8 = Mira Meeus | last8 = Castro Marrero | first8 = Jesus | author-link8 = Jesús Castro-Marrero | last9 = Nora-Krukle | first9 = Zaiga | author-link9 = Zaiga Nora-Krukle | last10 = Oltra | first10 = Elisa | author-link10 = Elisa Oltra | last11 =  Strand | first11 = Elin Bolle | author-link11 = Elin Bolle Strand | last12 =  Shikova | first12 =  Evelina | author-link12 =  Evelina Shikova | last13 =  Sekulic | first13 = Slobodan | author-link13 = Slobodan Sekulic | last14 = Murovska | first14 = Modra | author-link14 = Modra Murovska | date = 2017-07-26 | title = The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE| url = https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-017-1263-z|journal=Journal of Translational Medicine|language=en|volume=15|issue=1| pages=|doi=10.1186/s12967-017-1263-z|issn=1479-5876|pmc=5530475|pmid=28747192|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530475/ (Full Text)]
*2018, Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns<ref>{{Cite journal | last = Trivedi | first = Malav S. | last2 = Oltra | first2 = Elisa | authorlink2 = Elisa Oltra | last3 = Sarria | first3 = Leonor | last4 = Rose | first4 = Natasha | last5 = Beljanski | first5 = Vladimir | last6 = Fletcher | first6 = Mary Ann | author-link6 = Mary Ann Fletcher | last7 = Klimas | first7 = Nancy G. | author-link8 = Nancy Klimas | last8 = Nathanson | first8 = Lubov | author-link8 = Lubov Nathanson | date = Jul 2018 | title = Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns |url =http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201066|journal=PlosOne|volume=| pages=|doi=10.1371/journal.pone.0201066|via=}}</ref> - [[pubmed:30036399|(Full Text)]]
*2018, Unraveling the Molecular Determinants of Manual Therapy: An Approach to Integrative Therapeutics for the Treatment of [[Fibromyalgia]] and [[ME/CFS|Chronic Fatigue Syndrome/Myalgic Encephalomyelitis]]<ref>{{Cite journal | last = Espejo | first = José | last2 = García-Escudero | first2 = María | last3 = Oltra | first3 = Elisa | authorlink3 = Elisa Oltra | date = 2018-09-09 | title = Unraveling the Molecular Determinants of Manual Therapy: An Approach to Integrative Therapeutics for the Treatment of Fibromyalgia and Chronic Fatigue Syndrome/Myalgic Encephalomyelitis |url =https://www.mdpi.com/1422-0067/19/9/2673|journal=International Journal of Molecular Sciences|language=en|volume=19|issue=9 | pages = 2673|doi=10.3390/ijms19092673|via=}}</ref> - [https://www.mdpi.com/1422-0067/19/9/2673/htm (Full text)]
*2018, Culturing Adult Stem Cells for Cell-Based Therapeutics: Neuroimmune Applications<ref>{{Cite web |  url = https://cdn.intechopen.com/pdfs/63496.pdf | title=Culturing adult stem cells for cell-based therapeutics: Neuroimmune Applications | last = Moreno-Manzano | first = Victoria | last2 = Oltra Garcia | first2 = Elisa | authorlink2 = Elisa Oltra | date = 2018-11-05 | website = | archive-url = | archive-date = |url-status = | access-date=2018-11-16}}</ref> - [https://cdn.intechopen.com/pdfs/63496.pdf (Full text)]
*2019, Impact of Polypharmacy on Candidate Biomarker miRNomes for the Diagnosis of Fibromyalgia and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Striking back on Treatments<ref>{{Cite journal | last = Eloy Almenar-Pérez | first = | author-link = | last2 = Sánchez-Fito | first2 = Teresa | authorlink2 = | last3 = Ovejero | first3 = Tamara | authorlink3 = | last4 = Nathanson | first4 = Lubov | authorlink4 = | last5 = Oltra | first5 = Elisa | authorlink5 = Elisa Oltra | date = 14 February 2019 | title = Impact of Polypharmacy on Candidate Biomarker miRNomes for the Diagnosis of Fibromyalgia and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Striking back on Treatments |url =https://www.preprints.org/manuscript/201902.0134/v1|journal=Preprints|volume=|issue=2019020134| pages=|doi=10.20944/preprints201902.0134.v1|quote=|via=}}</ref> - [https://www.preprints.org/manuscript/201902.0134/v1 (Abstract)]
*2019, Epigenetic Components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover Potential Transposable Element Activation<ref>{{Cite journal | last = Almenar-Pérez | first = Eloy  | author-link = | last2 = Ovejero | first2 = Tamara | authorlink2 = | last3 = Sánchez-Fito | first3 = Teresa | authorlink3 = | last4 = Espejo | first4 = José A. | authorlink4 = | last5 = Nathanson | first5 = Lubov | authorlink5 = Lubov Nathanson | last6 = Oltra | first6 = Elisa | author-link6 = Elisa Oltra | date = Apr 2019 | title = Epigenetic Components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover Potential Transposable Element Activation | url =https://linkinghub.elsevier.com/retrieve/pii/S0149291819300724|journal=Clinical Therapeutics|language=en|volume=41|issue=4 | pages = 675–698|doi=10.1016/j.clinthera.2019.02.012|quote=|via=}}</ref> - [https://www.clinicaltherapeutics.com/article/S0149-2918(19)30072-4/fulltext (Full text)]
*2020, Assessing diagnostic value of microRNAs from peripheral [[blood]] mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome<ref>{{Cite journal | last = Almenar-Pérez | first = Eloy  | author-link = | last2 = Sarría | first2 = Leonor | authorlink2 = | last3 = Nathanson | first3 = Lubov | authorlink3 = Lubov Nathanson | last4 = Oltra | first4 = Elisa | authorlink4 = Elisa Oltra | date = Dec 2020 | title = Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | url =http://www.nature.com/articles/s41598-020-58506-5|journal=Scientific Reports|language=en|volume=10|issue=1 | pages = 2064|doi=10.1038/s41598-020-58506-5|issn=2045-2322|pmc=|pmid=|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005890/ (Full text)]
*2020, Unravelling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Gender‐specific changes in the microRNA expression profiling in ME/CFS<ref name="Cheema2020">{{Cite journal | last = Cheema | first = Amanpreet K.  | author-link = | last2 = Sarria | first2 = Leonor | authorlink2 = | last3 = Bekheit | first3 = Mina | authorlink3 = | last4 = Collado | first4 = Fanny | authorlink4 = Fanny Collado | last5 = Almenar‐Pérez | first5 = Eloy | authorlink5 = | last6 = Martín‐Martínez | first6 = Eva | author-link6 = | last7 = Alegre | first7 = Jose | author-link8 = José Alegre | last8 = Castro‐Marrero | first8 = Jesus | author-link8 = Jesús Castro-Marrero | last9 = Fletcher | first9 = Mary A. | author-link9 = Mary Ann Fletcher | date = Apr 14, 2020 | title = Unravelling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Gender-specific changes in the microRNA expression profiling in ME/CFS| url = https://onlinelibrary.wiley.com/doi/abs/10.1111/jcmm.15260|journal=Journal of Cellular and Molecular Medicine|language=en|volume=00|issue= | pages = 1-13|doi=10.1111/jcmm.15260|issn=1582-4934|pmc=|pmid=32291908|access-date=|quote=|via= | last10 = Klimas | first10 = Nancy | author-link10 = Nancy Klimas | last11 = Oltra | first11 = Elisa | author-link11 = Elisa Oltra | last12 = Nathanson | first12 = Lubov | author-link12 = Lubov Nathanson}}</ref> - [https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.15260 (Full text)]


==Talks & interviews==
==Talks and interviews==
*2016, Speaker at the 11th [[Invest in ME International ME Conference]] on "Molecular Biomarkers of Myalgic Encephalomyelitis"<ref>http://www.investinme.eu/IIMEC11.shtml#agenda</ref> [http://www.investinme.eu/IIMEC11.shtml#dvd DVD available]
*2016, Speaker at the 11th [[Invest in ME International ME Conference]] on "Molecular Biomarkers of Myalgic Encephalomyelitis"<ref>{{Cite web |  url = http://investinme.org/cindex.shtml | title = UK Charity for Myalgic Encephalomyelitis Centre of Excellence for ME Blog|website=investinme.org|access-date=2019-07-16}}</ref> - [http://www.investinme.org/IIMEC11.shtml#dvd DVD available]
*2018, [[CFS/ME Research Collaborative Conference|UK CFS/ME Research Collaborative Conference]] - ''[https://www.youtube.com/watch?v=RBUBumL6wuo&index=15&list=PLJV2oZMsotONY3AEkA-c3kVFjtVokLBD7 MRC Funded Update: Persistent fatigue induced by interferon-alpha: a novel, inflammation-based, proxy model of Chronic Fatigue Syndrome]''


==See Also==
==See also==
*[[EUROMENE]]
*[[Invest in ME International ME Conference]]
*[[Invest in ME International ME Conference]]
*[[EUROMENE]]


==References==
==References==
<references>
{{reflist}}
<ref name="EUROMENE2017">
{{citation
| last1  = Scheibenbogen    | first1 = Carmen          | authorlink1 = Carmen Scheibenbogen
| last2  = Freitag          | first2 = Helma          | authorlink2 = Helma Freitag
| last3  = Blanco          | first3 = Julià          | authorlink3 = Julià Blanco
| last4  = Capelli          | first4 = Enrica          | authorlink4 = Enrica Capelli
| last5  = Lacerda          | first5 = Eliana          | authorlink5 = Eliana Lacerda
| last6  = Authier          | first6 = Jerome          | authorlink6 = Jerome Authier
| last7  = Meeus            | first7 = Mira            | authorlink7 = Mira Meeus
| last8  = Castro Marrero  | first8 = Jesus          | authorlink8 = Jesus Castro-Marrero
| last9  = Nora-Krukle      | first9 = Zaiga          | authorlink9 = Zaiga Nora-Krukle
| last10  = Oltra            | first10 = Elisa          | authorlink10 = Elisa Oltra
| last11  = Bolle Strand    | first11 = Elin          | authorlink11 = Elin Bolle Strand
| last12  = Shikova          | first12 = Evelina        | authorlink12 = Evelina Shikova
| last13  = Sekulic          | first13 = Slobodan      | authorlink13 = Slobodan Sekulic
| last14  = Murovska        | first14 = Modra          | authorlink14 = Modra Murovska
| title  = The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE
| journal = Journal of Translational Medicine | volume = 15 | page = 162
| date    = 2017
| doi    = 10.1186/s12967-017-1263-z
}}
</ref>
</references>


[[Category:Researchers]] [[Category:Spain researchers]][[Category:Psychological paradigm critics]]
[[Category:Researchers]]  
[[Category:Spain researchers]]
[[Category:Psychological paradigm critics]]
[[Category:PACE trial critics]]
[[Category:PACE trial critics]]

Latest revision as of 13:44, July 25, 2023

Source: www.researchgate.net

Elisa Oltra, aka Elisa Oltra Garcia, PhD., is a professor of Cell and Molecular Biology at the Universidad Católica de Valencia "San Vicente Mártir", Valencia, Spain. Her areas of research include stem cell, cancer, fibromyalgia and genetics.[1][2]

2017 Ramsay Award[edit | edit source]

A team comprised of Dr. Elisa Oltra of Universidad Católica de Valencia, Spain, and Drs. Lubov Nathanson, Vladimir Beljanski and Malav Suchin Trivedi of Nova Southeastern University, US, were awarded a 2017 Ramsay Award grant from the Solve ME/CFS Initiative for researching the effect of ME/CFS on epigenetic regulation in specific immune cell types.[3]

Committees and working groups[edit | edit source]

ME/CFS Common Data Element (CDE) Project[edit | edit source]

Chair of the Biomarkers Working Group and a member of the Baseline/Covariate Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke and the Centers for Disease Control and Prevention.[4]

EUROMENE[edit | edit source]

Participating member of the Biomarkers Working Group of EUROMENE, a European Union, COST Action CA15111, not-for-profit research organization committed to tackling the cause and treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.[5]

Notable studies[edit | edit source]

  • 2017, The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE[6] - (Full Text)
  • 2018, Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns[7] - (Full Text)
  • 2018, Unraveling the Molecular Determinants of Manual Therapy: An Approach to Integrative Therapeutics for the Treatment of Fibromyalgia and Chronic Fatigue Syndrome/Myalgic Encephalomyelitis[8] - (Full text)
  • 2018, Culturing Adult Stem Cells for Cell-Based Therapeutics: Neuroimmune Applications[9] - (Full text)
  • 2019, Impact of Polypharmacy on Candidate Biomarker miRNomes for the Diagnosis of Fibromyalgia and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Striking back on Treatments[10] - (Abstract)
  • 2019, Epigenetic Components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover Potential Transposable Element Activation[11] - (Full text)
  • 2020, Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[12] - (Full text)
  • 2020, Unravelling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Gender‐specific changes in the microRNA expression profiling in ME/CFS[13] - (Full text)

Talks and interviews[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. ↑ "ELISA OLTRA | PhD | Catholic University of Valencia "San Vicente Martir", Valencia | Biomedicine". ResearchGate. Retrieved February 18, 2020.
  2. ↑ "Elisa Oltra García: "Trabajamos en el desarrollo de un test válido y objetivo para el diagnóstico de la fibromialgia"". oei.es. Retrieved May 2, 2019.
  3. ↑ "2017 Ramsay Award Program Results". Solve ME/CFS Initiative. Retrieved May 2, 2019.
  4. ↑ "Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster". NIH. Retrieved October 11, 2019.
  5. ↑ "Action CA15111". COST. Retrieved July 16, 2019.
  6. ↑ Scheibenbogen, Carmen; Freitag, Helma; Blanco, Julià; Capelli, Enrica; Lacerda, Eliana; Authier, Jerome; Meeus, Mira; Castro Marrero, Jesus; Nora-Krukle, Zaiga; Oltra, Elisa; Strand, Elin Bolle; Shikova, Evelina; Sekulic, Slobodan; Murovska, Modra (July 26, 2017). "The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE". Journal of Translational Medicine. 15 (1). doi:10.1186/s12967-017-1263-z. ISSN 1479-5876. PMC 5530475. PMID 28747192.
  7. ↑ Trivedi, Malav S.; Oltra, Elisa; Sarria, Leonor; Rose, Natasha; Beljanski, Vladimir; Fletcher, Mary Ann; Klimas, Nancy G.; Nathanson, Lubov (July 2018). "Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns". PlosOne. doi:10.1371/journal.pone.0201066.
  8. ↑ Espejo, José; García-Escudero, María; Oltra, Elisa (September 9, 2018). "Unraveling the Molecular Determinants of Manual Therapy: An Approach to Integrative Therapeutics for the Treatment of Fibromyalgia and Chronic Fatigue Syndrome/Myalgic Encephalomyelitis". International Journal of Molecular Sciences. 19 (9): 2673. doi:10.3390/ijms19092673.
  9. ↑ Moreno-Manzano, Victoria; Oltra Garcia, Elisa (November 5, 2018). "Culturing adult stem cells for cell-based therapeutics: Neuroimmune Applications" (PDF). Retrieved November 16, 2018.
  10. ↑ Eloy Almenar-Pérez; Sánchez-Fito, Teresa; Ovejero, Tamara; Nathanson, Lubov; Oltra, Elisa (February 14, 2019). "Impact of Polypharmacy on Candidate Biomarker miRNomes for the Diagnosis of Fibromyalgia and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Striking back on Treatments". Preprints (2019020134). doi:10.20944/preprints201902.0134.v1.
  11. ↑ Almenar-Pérez, Eloy; Ovejero, Tamara; Sánchez-Fito, Teresa; Espejo, José A.; Nathanson, Lubov; Oltra, Elisa (April 2019). "Epigenetic Components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover Potential Transposable Element Activation". Clinical Therapeutics. 41 (4): 675–698. doi:10.1016/j.clinthera.2019.02.012.
  12. ↑ Almenar-Pérez, Eloy; Sarría, Leonor; Nathanson, Lubov; Oltra, Elisa (December 2020). "Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Scientific Reports. 10 (1): 2064. doi:10.1038/s41598-020-58506-5. ISSN 2045-2322.
  13. ↑ Cheema, Amanpreet K.; Sarria, Leonor; Bekheit, Mina; Collado, Fanny; Almenar‐Pérez, Eloy; Martín‐Martínez, Eva; Alegre, Jose; Castro‐Marrero, Jesus; Fletcher, Mary A.; Klimas, Nancy; Oltra, Elisa; Nathanson, Lubov (April 14, 2020). "Unravelling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Gender-specific changes in the microRNA expression profiling in ME/CFS". Journal of Cellular and Molecular Medicine. 00: 1–13. doi:10.1111/jcmm.15260. ISSN 1582-4934. PMID 32291908.
  14. ↑ "UK Charity for Myalgic Encephalomyelitis Centre of Excellence for ME Blog". investinme.org. Retrieved July 16, 2019.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

extracellular vesicle An extracellular vesicle (sometimes abbreviated EV) is a piece of a cell that has broken off and formed a separate membrane-bound vesicle. A membrane-bound vesicle is like a bubble, or like a mini-cell, in that it has a membrane surrounding some liquid. An extracellular vesicle may also contain some parts of the cell from which the extracellular vesicle arose. There are currently two types of extracellular vesicles: "exosomes" and "microvesicles". An "exosome" is an extracellular vesicle that began inside the cell as an intracellular vesicle known as an "endosome". A "microvesicle" is an extracellular vesicle that begins at the cell surface, and pinches off the cell's own membrane to form a separate vesicle. (Learn more: journals.physiology.org)

National Institutes of Health (NIH) - A set of biomedical research institutes operated by the U.S. government, under the auspices of the Department of Health and Human Services.

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