Ekua Brenu: Difference between revisions

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{{Citation | last = Hardcastle | first1 = SL| authorlink1 = Sharni Hardcastle | last2 = Brenu | first2 = EW| authorlink2 = Ekua Brenu | last3 = Johnston| first3 = S | authorlink3 = | last4 =Nguyen | first4 = T | authorlink4 = | last5 = Huth | first5 = T | authorlink5 = Teilah Huth | last6 = Wong | first6 = N | authorlink6 = | last7 = Ramos | first7 = S | authorlink7 = Sandra Ramos | last8 =Staines | first8 = DR| authorlink8 = Donald Staines | last9 = Marshall-Gradisnik | first9 = SM| authorlink9 = Sonya Marshall-Gradisnik  | title = Serum Immune Proteins in Moderate and Severe Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients | journal =International Journal of Medical Sciences  | volume = 12  | issue = 10 | pages = 764-772 | date = 2015 | doi = 10.7150/ijms.12399 }}</ref>
{{Citation | last = Hardcastle | first1 = SL| authorlink1 = Sharni Hardcastle | last2 = Brenu | first2 = EW| authorlink2 = Ekua Brenu | last3 = Johnston| first3 = S | authorlink3 = | last4 =Nguyen | first4 = T | authorlink4 = | last5 = Huth | first5 = T | authorlink5 = Teilah Huth | last6 = Wong | first6 = N | authorlink6 = | last7 = Ramos | first7 = S | authorlink7 = Sandra Ramos | last8 =Staines | first8 = DR| authorlink8 = Donald Staines | last9 = Marshall-Gradisnik | first9 = SM| authorlink9 = Sonya Marshall-Gradisnik  | title = Serum Immune Proteins in Moderate and Severe Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients | journal =International Journal of Medical Sciences  | volume = 12  | issue = 10 | pages = 764-772 | date = 2015 | doi = 10.7150/ijms.12399 }}</ref>
<ref name="Huth, 2014">
<ref name="Huth, 2014">
{{Citation | last = Huth | first1 = Teilah K.  | authorlink1 = Teilah Huth | last2 = Brenu | first2 = Ekua  | authorlink2 = Ekua Brenu | last3 = Nguyen| first3 = Thao  | authorlink3 = | last4 =Hardcastle | first4 = Sharni L.  | authorlink4 = Sharni Hardcastle | last5 = Johnston | first5 = Samantha| authorlink5 = | last6 = Ramos | first6 = Sandra  | authorlink6 = Sandra Ramos | last7 = Staines | first7 = Donald R.  | authorlink7 = Donald Staines | last8 =Marshall-Gradisnik | first8 = Sonya M.| authorlink8 = Sonya Marshall-Gradisnik | title = Characterization of Natural Killer Cell Phenotypes in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis | journal = Journal of Clinical & Cellular Immunology | volume = 5 | issue = 3  | page = | date = 2014 | pmid =  | doi = 10.4172/2155-9899.1000223 }}</ref>
{{Citation | last = Huth | first1 = Teilah K.  | authorlink1 = Teilah Huth | last2 = Brenu | first2 = Ekua  | authorlink2 = Ekua Brenu | last3 = Nguyen| first3 = Thao  | authorlink3 = | last4 =Hardcastle | first4 = Sharni L.  | authorlink4 = Sharni Hardcastle | last5 = Johnston | first5 = Samantha| authorlink5 = | last6 = Ramos | first6 = Sandra  | authorlink6 = Sandra Ramos | last7 = Staines | first7 = Donald R.  | authorlink7 = Donald Staines | last8 =Marshall-Gradisnik | first8 = Sonya M. | authorlink8 = Sonya Marshall-Gradisnik | title = Characterization of Natural Killer Cell Phenotypes in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis | journal = Journal of Clinical & Cellular Immunology | volume = 5 | issue = 3  | page = | date = 2014 | pmid =  | doi = 10.4172/2155-9899.1000223 }}</ref>
<ref name="HuthTK2016">{{citation | last = Huth | first1 = TK | authorlink1 = Teilah Huth | last2 = Brenu | first2 = EW  | authorlink2 = Ekua Brenu | last3 = Ramos | first3 = S | authorlink3 = Sandra Ramos | last4 =Nguyen | first4 = T | authorlink4 = | last5 = Broadley | first5 = S | authorlink5 = | last6 = Staines | first6 = D | authorlink6 = Donald Staines | last7 = Marshall-Gradisnik | first7 = S | authorlink7 = Sonya Marshall-Gradisnik | title = Pilot Study of Natural Killer Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis | journal =Scand J Immunol | date = Jan 2016 | volume = 83 | issue = 1 | page = 44-51 | pmid = 26381393 | doi = 10.1111/sji.12388 | url = https://www.ncbi.nlm.nih.gov/pubmed/26381393 }}</ref>
<ref name="HuthTK2016">{{citation | last = Huth | first1 = TK | authorlink1 = Teilah Huth | last2 = Brenu | first2 = EW  | authorlink2 = Ekua Brenu | last3 = Ramos | first3 = S | authorlink3 = Sandra Ramos | last4 =Nguyen | first4 = T | authorlink4 = | last5 = Broadley | first5 = S | authorlink5 = | last6 = Staines | first6 = D | authorlink6 = Donald Staines | last7 = Marshall-Gradisnik | first7 = S | authorlink7 = Sonya Marshall-Gradisnik | title = Pilot Study of Natural Killer Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis | journal =Scand J Immunol | date = Jan 2016 | volume = 83 | issue = 1 | page = 44-51 | pmid = 26381393 | doi = 10.1111/sji.12388 | url = https://www.ncbi.nlm.nih.gov/pubmed/26381393 }}</ref>
<ref name="Johnston, 2013">
<ref name="Johnston, 2013">
{{Citation | last = Johnston | first1 = S. C.  | authorlink1 = | last2 = Brenu | first2 = E. W.  | authorlink2 = Ekua Brenu | last3 = Staines | first3 =D. R.  | authorlink3 = Donald Staines | last4 =Marshall-Gradisnik | first4 = S. M.  | authorlink4 = Sonya Marshall-Gradisnik | title = The role of clinical guidelines for chronic fatigue syndrome/myalgic encephalomyelitis in research settings | journal =Fatigue: Biomedicine, Health & Behavior  | volume = 2  | issue = 1 | page = 28-39 | date = 2013 | pmid =  | doi = 10.1080/21641846.2013.860779 }}</ref>
{{Citation | last = Johnston | first1 = S. C.  | authorlink1 = | last2 = Brenu | first2 = E. W.  | authorlink2 = Ekua Brenu | last3 = Staines | first3 = D.R.  | authorlink3 = Donald Staines | last4 =Marshall-Gradisnik | first4 = S. M.  | authorlink4 = Sonya Marshall-Gradisnik | title = The role of clinical guidelines for chronic fatigue syndrome/myalgic encephalomyelitis in research settings | journal =Fatigue: Biomedicine, Health & Behavior  | volume = 2  | issue = 1 | page = 28-39 | date = 2013 | pmid =  | doi = 10.1080/21641846.2013.860779 }}</ref>
<ref name="Marshall-Gradisnik, 2015">
<ref name="Marshall-Gradisnik, 2015">
{{Citation | last = Marshall-Gradisnik | first1 = Sonya M.  | authorlink1 =  Sonya Marshall-Gradisnik | last2 = Smith | first2 = Peter  | authorlink2 = | last3 = Brenu| first3 = Ekua W.| authorlink3 = Ekua Brenu | last4 =Nilius | first4 = Bernd  | authorlink4 = | last5 = Ramos | first5 = Sandra B. | authorlink5 = Sandra Ramos | last6 = Staines | first6 = Donald R. | authorlink6 = Donald Staines  | title = Examination of Single Nucleotide Polymorphisms (SNPs) in Transient Receptor Potential (TRP) Ion Channels in Chronic Fatigue Syndrome Patients | journal =Immunology and Immunogenetics Insights | volume = 7 | issue = 2015 | page = 1-6 | date = 2015 | pmid =  | doi =  10.4137/III.S25147 | url = http://insights.sagepub.com/examination-of-single-nucleotide-polymorphisms-snps-in-transient-recep-article-a4824 }}</ref>
{{Citation | last = Marshall-Gradisnik | first1 = Sonya M.  | authorlink1 =  Sonya Marshall-Gradisnik | last2 = Smith | first2 = Peter  | authorlink2 = | last3 = Brenu| first3 = Ekua W. | authorlink3 = Ekua Brenu | last4 =Nilius | first4 = Bernd  | authorlink4 = | last5 = Ramos | first5 = Sandra B. | authorlink5 = Sandra Ramos | last6 = Staines | first6 = Donald R. | authorlink6 = Donald Staines  | title = Examination of Single Nucleotide Polymorphisms (SNPs) in Transient Receptor Potential (TRP) Ion Channels in Chronic Fatigue Syndrome Patients | journal =Immunology and Immunogenetics Insights | volume = 7 | issue = 2015 | page = 1-6 | date = 2015 | pmid =  | doi =  10.4137/III.S25147 | url = http://insights.sagepub.com/examination-of-single-nucleotide-polymorphisms-snps-in-transient-recep-article-a4824 }}</ref>
<ref name="Peterson, 2015">
<ref name="Peterson, 2015">
{{Citation | last = Peterson | first1 = D  | authorlink1 = Daniel Peterson | last2 = Brenu | first2 = EW  | authorlink2 = Ekua Brenu | last3 = Gottschalk | first3 = G | authorlink3 = Gunnar Gottschalk | last4 =Ramos | first4 = SB  | authorlink4 = Sandra Ramos | last5 = Nguyen | first5 = T | authorlink5 = | last6 = Staines | first6 = D | authorlink6 = Donald Staines | last7 = Marshall-Gradisnik | first7 = S | authorlink7 = Sonya Marshall-Gradisnik | title = Cytokines in the Cerebrospinal Fluids of Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis | journal =Mediators of Inflammation  | volume = | issue = 2015  | pages = 929720 | date = 2015 | doi = 10.1155/2015/929720 }}</ref>
{{Citation | last = Peterson | first1 = D  | authorlink1 = Daniel Peterson | last2 = Brenu | first2 = EW  | authorlink2 = Ekua Brenu | last3 = Gottschalk | first3 = G | authorlink3 = Gunnar Gottschalk | last4 =Ramos | first4 = SB  | authorlink4 = Sandra Ramos | last5 = Nguyen | first5 = T | authorlink5 = | last6 = Staines | first6 = D | authorlink6 = Donald Staines | last7 = Marshall-Gradisnik | first7 = S | authorlink7 = Sonya Marshall-Gradisnik | title = Cytokines in the Cerebrospinal Fluids of Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis | journal =Mediators of Inflammation  | volume = | issue = 2015  | pages = 929720 | date = 2015 | doi = 10.1155/2015/929720 }}</ref>

Revision as of 16:53, November 30, 2022

Ekua Weba Brenu, PhD, is a post-doctorate researcher at the School of Medical Science, Griffith University, Griffith Health Institute, and a Senior Research Fellow at the National Centre for Neuroimmunology and Emerging Diseases, Gold Coast, Queensland, Australia.[1]

Awards[edit | edit source]

  • 2011, Junior Investigator Award to encourage young CFS/FM researchers in recognition of their work awarded by IACFSME.[2]

Diagnostic biomarker[edit | edit source]

In 2015, Griffith University filed for a patent for a biological marker (Patent Publication number WO2016023077 A1) for the diagnosis and management of ME and CFS. Sonya Marshall-Gradisnik and Ekua Brenu are listed as the inventors. The patent application states: "The present invention resides broadly in the use of at least one miRNA as a biological marker for identifying or diagnosing a subject having CFS and/or ME." Very simply stated, microRNA (miRNA) are molecules involved in gene expression. They are different from mRNA which stands for messenger RNA.[3] In 2016, Griffith University's Professor Donald Staines and Professor Sonya Marshall-Gradisnik announced that they have been awarded a $4-million grant to be administered during the next five years that will enable them to continue research into developing a diagnostic test for ME/CFS.[4]

Notable studies in ME/CFS[edit | edit source]

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. https://www.griffith.edu.au/health/national-centre-neuroimmunology-emerging-diseases/our-team
  2. "IACFS/ME Awardees". IACFS/ME. Retrieved April 23, 2020.
  3. https://www.google.co.uk/patents/WO2016023077A1?cl=en&dq=sonya+marshall-gradisnik
  4. http://www.goldcoastbulletin.com.au/lifestyle/gold-coast-team-getting-closer-to-discovering-test-for-chronic-fatigue-syndrom/news-story/1627b3fcc41c53efac927200a53cc756
  5. Brenu, EW; van Driel, ML; Staines, DR; Ashton, KJ; Ramos, SB; Keane, J; Klimas, NG; Marshall-Gradisnik, SM (2011), "Immunological abnormalities as potential biomarkers in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis", Journal of Translational Medicine, 9 (81), doi:10.1186/1479-5876-9-81
  6. Brenu, Ekua W; van Driel, Mieke L; Staines, Donald R; Ashton, Kevin J; Hardcastle, Sharni L; Keane, James; Tajouri, Lotti; Peterson, Daniel; Ramos, Sandra B; Marshall-Gradisnik, Sonya M (2012), "Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis", Journal of Translational Medicine, 10: 88, doi:10.1186/1479-5876-10-88
  7. Brenu, EW; Ashton, KJ; van Driel, M; Staines, D; Peterson, D; Atkinson, GM; Marshall-Gradisnik, S (2012), "Cytotoxic lymphocyte microRNAs as prospective biomarkers for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis.", Journal of Affective Disorders, 141 (2–3): 261-269, doi:10.1016/j.jad.2012.03.037
  8. Brenu, Ekua W; van Driel, Mieke L; Staines, Donald R; Kreijkamp-Kaspers, Sanne; Hardcastle, Sharni L; Marshall-Gradisnik, Sonya M (2012), "The Effects of Influenza Vaccination on Immune Function in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis" (PDF), International Journal of Clinical Medicine, 3 (6): 544-551, doi:10.4236/ijcm.2012.36098
  9. Johnston, S. C.; Brenu, E. W.; Staines, D.R.; Marshall-Gradisnik, S. M. (2013), "The role of clinical guidelines for chronic fatigue syndrome/myalgic encephalomyelitis in research settings", Fatigue: Biomedicine, Health & Behavior, 2 (1): 28-39, doi:10.1080/21641846.2013.860779
  10. Brenu, EW; Huth, TK; Hardcastle, SL; Fuller, K; Kaur, M; Johnston, S; Ramos, S; Staines, D; Marshall-Gradisnik, S (2014), "The Role of adaptive and innate immune cells in chronic fatigue syndrome/myalgic encephalomyelitis", International Immunology, 26 (4): 233-42, doi:10.1093/intimm/dxt068, PMID 24343819
  11. Huth, Teilah K.; Brenu, Ekua; Nguyen, Thao; Hardcastle, Sharni L.; Johnston, Samantha; Ramos, Sandra; Staines, Donald R.; Marshall-Gradisnik, Sonya M. (2014), "Characterization of Natural Killer Cell Phenotypes in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis", Journal of Clinical & Cellular Immunology, 5 (3), doi:10.4172/2155-9899.1000223
  12. Hardcastle, Sharni Lee; Brenu, Ekua Weba; Johnston, Samantha; Nguyen, Thao; Huth, Teilah; Kaur, Manprit; Ramos, Sandra; Salajegheh, Ali; Staines, Donald R; Marshall-Gradisnik, Sonya (2014), "Analysis of the Relationship between Immune Dysfunction and Symptom Severity in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)", Journal of Clinical & Cellular Immunology, 5 (190), doi:10.4172/2155-9899.1000190
  13. Wong, Naomi; Nguyen, Thao; Brenu, Ekua Weba; Broadley, Simon; Staines, Donald; Marshall-Gradisnik, Sonya (2015), "A Comparison of Cytokine Profiles of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis Patients", International Journal of Clinical Medicine, 6 (10): 769-783, doi:10.4236/ijcm.2015.610103
  14. Hardcastle, SL; Brenu, EW; Johnston, S; Nguyen, T; Huth, T; Wong, N; Ramos, S; Staines, DR; Marshall-Gradisnik, SM (2015), "Serum Immune Proteins in Moderate and Severe Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients", International Journal of Medical Sciences, 12 (10): 764–772, doi:10.7150/ijms.12399
  15. Hardcastle, SL; Brenu, EW; Johnston, S; Nguyen, T; Huth, T; Wong, N; Ramos, S; Staines, DR; Marshall-Gradisnik, SM (2015), "Characterisation of cell functions and receptors in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)", BMC Immunology, 16 (35), doi:10.1186/s12865-015-0101-4
  16. Marshall-Gradisnik, Sonya M.; Smith, Peter; Brenu, Ekua W.; Nilius, Bernd; Ramos, Sandra B.; Staines, Donald R. (2015), "Examination of Single Nucleotide Polymorphisms (SNPs) in Transient Receptor Potential (TRP) Ion Channels in Chronic Fatigue Syndrome Patients", Immunology and Immunogenetics Insights, 7 (2015): 1-6, doi:10.4137/III.S25147
  17. Hardcastle, Sharni Lee; Brenu, Ekua Weba; Johnston, Samantha; Nguyen, Thao; Huth, Teilah; Ramos, Sandra; Staines, Donald; Marshall-Gradisnik, Sonya (2015), "Longitudinal analysis of immune abnormalities in varying severities of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients", Journal of Translational Medicine, 13 (299), doi:10.1186/s12967-015-0653-3
  18. Peterson, D; Brenu, EW; Gottschalk, G; Ramos, SB; Nguyen, T; Staines, D; Marshall-Gradisnik, S (2015), "Cytokines in the Cerebrospinal Fluids of Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis", Mediators of Inflammation (2015): 929720, doi:10.1155/2015/929720
  19. Ramos, S; Brenu, E; Broadley, S; Kwiatek, R; Ng, J; Nguyen, T; Freeman, S; Staines, D; Marshall-Gradisnik, S (March 20, 2016), "Regulatory T, natural killer T and γδ T cells in multiple sclerosis and chronic fatigue syndrome/myalgic encephalomyelitis: a comparison" (PDF), Asian Pac J Allergy Immunol, 34 (2016): 300–305, doi:10.12932/AP0733
  20. Huth, TK; Brenu, EW; Ramos, S; Nguyen, T; Broadley, S; Staines, D; Marshall-Gradisnik, S (January 2016), "Pilot Study of Natural Killer Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis", Scand J Immunol, 83 (1): 44-51, doi:10.1111/sji.12388, PMID 26381393
  21. Brenu, EW; Broadley, S; Nguyen, T; Johnston, S; Ramos, S; Staines, D; Marshall-Gradisnik, S (January 4, 2016), "A Preliminary Comparative Assessment of the Role of CD8+ T Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis" (PDF), Journal of Immunology Research: 9064529, doi:10.1155/2016/9064529
  22. https://www.griffith.edu.au/__data/assets/pdf_file/0009/566118/CFS-Symposium-2013-Program.pdf