Eiren Sweetman

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Eiren Sweetman is a postdoctoral fellow and researcher at the University of Otago, New Zealand, with a special interest in ME/CFS.[1]

Notable studies[edit | edit source]

  • 2019, Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome[2] - (Full text)
  • 2019, Current Research Provides Insight into the Biological Basis and Diagnostic Potential for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)[3] - (Full text)
  • 2020, A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction[4] - (Full text)

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

  • Institution

References[edit | edit source]

  1. ↑ Sciences, Division of Health. "Profile | Division of Health Sciences". otago.ac.nz. Retrieved September 27, 2020.
  2. ↑ Sweetman, Eiren; Ryan, Margaret; Edgar, Christina; Mackay, Angus; Vallings, Rosamund; Tate, Warren (January 2019). "Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome". International Journal of Immunopathology and Pharmacology. 33. doi:10.1177/2058738418820402.
  3. ↑ Sweetman, Eiren; Noble, Alex; Edgar, Christina; Mackay, Angus; Helliwell, Amber; Vallings, Rosamund; Ryan, Margaret; Tate, Warren (July 10, 2019). "Current Research Provides Insight into the Biological Basis and Diagnostic Potential for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)". Diagnostics. 9 (3): 73. doi:10.3390/diagnostics9030073. ISSN 2075-4418.
  4. ↑ Sweetman, Eiren; Kleffmann, Torsten; Edgar, Christina; de Lange, Michel; Vallings, Rosamund; Tate, Warren (September 24, 2020). "A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction". Journal of Translational Medicine. 18 (1): 365. doi:10.1186/s12967-020-02533-3. ISSN 1479-5876. PMC 7512220.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

mitochondria Important parts of the biological cell, with each mitochondrion encased within a mitochondrial membrane. Mitochondria are best known for their role in energy production, earning them the nickname "the powerhouse of the cell". Mitochondria also participate in the detection of threats and the response to these threats. One of the responses to threats orchestrated by mitochondria is apoptosis, a cell suicide program used by cells when the threat can not be eliminated.

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