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Eicosanoid
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==Function== Eicosanoids are involved in vasodilation and vasoconstriction, promotion of sleep, pain and fever. They pay a role in up- or down-regulating inflammatory [[Cytokine|cytokines]]. What eicosanoids cells produce and their effects depend on the type of cell, the tissue in which that cell is found, and the cell's activation state. For example, those produced via the [[COX]] enzyme pathway generate the symptoms commonly associated with inflammation: heat, swelling, redness, and pain. Those produced via the [[LOX]] pathway tend to be associated with the leukotrienes involved in [[allergy]] and asthma. The same prostaglandin that causes pain signaling in the brain can lead to a decrease in inflammation in other parts of the body.<ref>http://www.ncbi.nlm.nih.gov/pubmed/26139350</ref>
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