Donald Lewis

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Revision as of 05:05, May 14, 2018 by Kmdenmark (talk | contribs) (added study and ref)
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Dr Donald P. Lewis is a general practitioner specialising in ME/CFS working in Melbourne, Australia. He has been treating patients with ME/CFS, and researching the condition, since 1985.

International Consensus Criteria[edit | edit source]

Dr Lewis is one of the authors of the 2011 case definition, International Consensus Criteria.[1]

Books[edit | edit source]

  • 2017, Chapter 31 - Sleep, Cognitive and Mood Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, in The Handbook of Stress and Health: A Guide to Research and Practice[2]

Notable studies[edit | edit source]

  • 2018, Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection[3]
  • 2018, Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons[4] (Full Text) (Correction)
  • 2017 - Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and d-lactic acidosis: a systematic review[5] (Full Text)
  • 2017 - The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome[6]
  • 2016 - Widespread pain and altered renal function in ME/CFS patients[7] (Abstract)
  • 2016 - Support for the Microgenderome: Associations in a Human Clinical Population[8] (Full Text)
  • 2015 - Sleep quality and the treatment of intestinal microbiota imbalance in Chronic Fatigue Syndrome: A pilot study[9] (Full text)
  • 2015 - Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients[10]
  • 2014 - Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort[11]
  • 2009 - Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome[12]

Clinic location[edit | edit source]

Dr Lewis founded the CFS Discovery clinic, which is in Donvale, Melbourne.

Talks and interviews[edit | edit source]

  • 2011 - Dr Don Lewis: Latest Understanding of ME/CFS (video)[13]

Online presence[edit | edit source]

  • Website
  • PubMed
  • Twitter
  • Facebook
  • YouTube

Learn more[edit | edit source]

  • Wikipedia
  • Institution

See also[edit | edit source]

References[edit | edit source]

  1. ↑ Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, A C P; Speight, N; Vallings, R; Bateman, L; Baumgarten-Austrheim, B; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Jo, D; Lewis, D; Light, A; Marshall-Gradisnik, S; Mena, I; Mikovits, JA; Miwa, K; Murovska, M; Pall, ML; Stevens, S (2011), "Myalgic encephalomyelitis: International Consensus Criteria.", Journal of Internal Medicine, 270 (4): 327-38, doi:10.1111/j.1365-2796.2011.02428.x, PMID 21777306
  2. ↑ Wallis, Amy; Jackson, Melinda L; Ball, Michelle; Lewis, Donald; Bruck, Dorothy (2017), Sleep, Cognitive and Mood Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, in The Handbook of Stress and Health: A Guide to Research and Practice, doi:10.1002/9781118993811.ch31
  3. ↑ Richardson, Alice; Lewis, Donald; Kita, Badia; Ludlow, Helen; Groome, Nigel; Hedger, Mark; de Kretser, David; Lidbury, Brett (2018), "Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection", Journal of Translational Medicine, 16: 97, doi:10.1186/s12967-018-1473-z
  4. ↑ Wallis, Amy; Ball, Michelle; Butt, Henry L; Lewis, Donald P; McKechnie, Sandra; Paull, Phillip; Jaa-Kwee, Amber; Bruck, Dorothy (2018), "Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons", Journal of Translational Medicine, 16 (1): 24, doi:10.1186/s12967-018-1392-z
  5. ↑ Wallis, Amy; Ball, Michelle; McKechnie, Sandra; Butt, Henry L; Lewis, Donald P; Bruck, Dorothy (2017), "Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and d-lactic acidosis: a systematic review", Journal of Translational Medicine, 2017 (15): 129, doi:10.1186/s12967-017-1229-1
  6. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (2017), "The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome", Metabolomics, 13 (1), doi:10.1007/s11306-016-1145-z
  7. ↑ McGregor, Neil R.; Armstrong, Christopher W.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (2016), "Widespread pain and altered renal function in ME/CFS patients", Fatigue: Biomedicine, Health & Behavior, 4 (3): 132-145, doi:10.1080/21641846.2016.1207400
  8. ↑ Wallis, Amy; Butt, Henry L; Ball, Michelle; Lewis, Donald P; Bruck, Dorothy (January 13, 2016), "Support for the Microgenderome: Associations in a Human Clinical Population", Scientific Reports, volume 6, article 19171, doi:10.1038/srep19171, PMID 26757840
  9. ↑ Jackson, Melinda L; Butt, Henry L; Ball, Michelle; Lewis, Donald P; Bruck, Dorothy (October 23, 2015), "Sleep quality and the treatment of intestinal microbiota imbalance in Chronic Fatigue Syndrome: A pilot study", Sleep Science, 2015 Nov, 8(3): 124-33, doi:10.1016/j.slsci.2015.10.001, PMID 26779319
  10. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (2015), "Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients", Metabolomics, 11 (6): 1626–1639, doi:10.1007/s11306-015-0816-5
  11. ↑ Reynolds, GK; Lewis, Donald P; Richardson, AM; Lidbury, Brett A (April 2014), "Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort", Journal of Internal Medicine, Volume 275, Issue 4: 409–417, doi:10.1111/joim.12161, PMID 24206536
  12. ↑ Sheedy, John R; Wettenhall, Richard EH; Scanlon, Denis; Gooley, Paul R; Lewis, Donald P; McGregor, Neil; Stapleton, David I; Butt, Henry L; De Meirleir, Kenny L (July 2009), "Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome", In Vivo, 2009 Jul-Aug, 23(4): 621-8, PMID 19567398
  13. ↑ Lewis, Donald P (May 2011), "Dr Don Lewis: Latest Understanding of ME/CFS (video)", Emerge Australia Seminar, Melbourne

cognition Thought processes, including attention, reasoning, and memory.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

stress Stress can by either physical or psychological, or both. Stress is either 1) a state of emotional or psychological strain or 2) the physical stress (pressure or tension) that a physical object such the human body is placed under, e.g., a stress test is a medical test that monitors the cardiovascular system during strenuous exercise.

microbiome The full collection of microscopic organisms (especially bacteria and fungi) which are present in a particular environment, particularly inside the human body.

serum The clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation. (Blood plasma is simply blood that has had its blood cells removed.)

metabolite A chemical compound produced by, or involved in, metabolism. The term is often used to refer to the degradation products of drugs in the body.

renal involving, related to or in the area of the kidneys

tachycardia An unusually rapid heart beat. Can be caused by exercise or illness. A symptom of postural orthostatic tachycardia syndrome (POTS). (Learn more: www.heart.org)

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

metabolomics The analysis of the chemical metabolism within cells, tissues or organisms. The term is often used to refer to the full set of metabolites found in a cell in a given environment.

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