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===Medical evidence=== For the purposes of Social Security Disability evaluation, in addition to a diagnosis of ME/CFS that meets the [[Fukuda criteria|Fukuda]] case definition, one or more of the following medical signs clinically documented over a period of at least 6 consecutive months is required to establish the existence of a medically determinable impairment (MDI) of [[Chronic fatigue syndrome|CFS]]:<ref name="Beyond" />{{Rp|260-261}} * palpably [[Swollen lymph nodes|swollen or tender lymph nodes]] on physical examination; * nonexudative [[pharyngitis]]; * persistent, reproducible muscle tenderness on repeated examinations, including the presence of positive tender points; or * any other medical signs that are consistent with medically accepted clinical practice and are consistent with the other evidence in the case record. For example, the [[Canadian Consensus Criteria]] (CCC) and [[International Consensus Criteria]] for [[Myalgic encephalomyelitis|ME]] (ME-ICC) explain that an acute [[Infection|infectious]] inflammatory event may precede the onset of CFS, and that other medical signs may be present, including ** frequent [[Viral infection|viral infections]] with prolonged recovery, ** [[sinusitis]], ** [[ataxia]], ** extreme [[pallor]], and ** pronounced weight change: [[Weight gain|gain]] or [[Weight loss|loss]].<ref name="Beyond"/>{{Rp|260-261}}
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