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Diagnostic biomarker
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=== Activin B === [[File:Blood-test-tubes.jpg|alt=Hand holding tubes choosing blood samples |thumb|300x300px|Blood tests are being developed to diagnose ME/CFS]] A 2017 study that used the [[Canadian Consensus Criteria]] (CCC) concludes: "Elevated [[activin B]] levels together with normal [[activin A]] levels identified patients with the diagnostic symptoms of [[CFS/ME]], thus providing a novel serum based test. The [[activin]]s have multiple physiological roles and capture the diverse array of symptoms experienced by CFS/ME patients."<ref name="Lidbury, 2017" /> The same group later used a weighted standing test in order to rate disease severity, and then compared subjects' health status to their levels of activin B. Activin B was once again found to separate people with ME/CFS from healthy controls.<ref>{{Cite journal | last = Richardson | first = Alice M. | last2 = Lewis | first2 = Don P. | last3 = Kita | first3 = Badia | last4 = Ludlow | first4 = Helen | last5 = Groome | first5 = Nigel P. | last6 = Hedger | first6 = Mark P. | last7 = de Kretser | first7 = David M. | last8 = Lidbury | first8 = Brett A. | date = 2018-04-12 | title = Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection | url =https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898049/|journal=Journal of Translational Medicine|volume=16|doi=10.1186/s12967-018-1473-z|issn=1479-5876|pmc=5898049|pmid=29650052}}</ref>
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