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Dauer
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=== Letter: Reply to Vogt et at.=== A letter by Vogt et at. (2016) challenged the conclusions drawn, stating that psychosocial or psychological causes could not be ruled and challenging the validity of the diagnosis of [[chronic fatigue syndrome]].<ref name="VogtLetter2016">{{Cite journal | last = Vogt | first = Henrik | last2 = Ulvestad | first2 = Elling | last3 = Wyller | first3 = Vegard Bruun | date = 2016-11-15 | title = Metabolic features of chronic fatigue syndrome revisited | url =https://www.pnas.org/content/113/46/E7140|journal=Proceedings of the National Academy of Sciences|language=en|volume=113|issue=46| pages = E7140βE7141|doi=10.1073/pnas.1615143113|issn=0027-8424|pmid=27810961}}</ref> Naviaux et al. replied that "... chemical details of the metabolic findings in ME/CFS led directly to a survey of other hypometabolic syndromes like dauer, diapause, torpor, hibernation, and caloric restriction. It was the detailed nature and specific pattern of abnormalities affecting six pathways (sphingolipids, phospholipids, purines, cholesterol, polyamines, and redox metabolism), and not the over 50 other biochemical pathways interrogated, that focused our attention on dauer. In dauer, there is a reprioritization of sensory processing that is metabolically controlled (9). This situation bears similarities to ME/CFS."<ref name="ReplyToVogt15112016">{{Cite journal | last = Naviaux | first = Robert K. | last2 = Naviaux | first2 = Jane C. | last3 = Li | first3 = Kefeng | last4 = Bright | first4 = A. Taylor | last5 = Alaynick | first5 = William A. | last6 = Wang | first6 = Lin | last7 = Baxter | first7 = Asha | last8 = Nathan | first8 = Neil | last9 = Anderson | first9 = Wayne | date = 2016-11-03 | title = Reply to Vogt et al.: Metabolomics and chronic fatigue syndrome | url =https://www.pnas.org/content/113/46/E7142|journal=Proceedings of the National Academy of Sciences|language=en|volume=113|issue=46| pages = E7142βE7143|doi=10.1073/pnas.1616261113|issn=0027-8424}}</ref>
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