Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Cytochrome P450 family 21 subfamily A member 2
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
'''Cytochrome P450 Family 21 Subfamily A Member 2''' or '''CYP21A2''' or '''CYP21A2 Mutation Associated Neuropsychiatric Spectrum''' (CAPS) might be able to predict the development of chronic illness. CYP21A2 is found within the [[RCCX Genetic Module Theory|RCCX gene module]], which some theorize is responsible for the myriad of differing signs and symptoms of [[myalgic encephalomyelitis]] (ME). The CYP21A2 [[Genetics of chronic fatigue syndrome|gene]] provides instructions for making an [[enzyme]] called 21-hydroxylase, which is part of the cytochrome P450 family of enzymes.<ref>{{Cite web | url = https://medlineplus.gov/genetics/gene/cyp21a2/ | title = CYP21A2 gene: MedlinePlus Genetics | last = | first = | authorlink = | date = | website = MedlinePlus Genetucs|language=en| archive-url = | archive-date = |url-status = | access-date=2021-03-11}}</ref> [[Cytochrome P450 2D6|Cytochrome P450]] enzymes are involved in many processes in the body, such as assisting with reactions that break down drugs and helping to produce cholesterol, certain [[hormone]]s, and fats (lipids). The 21-hydroxylase enzyme is found in the adrenal glands, which are located on top of the kidneys and produce a variety of hormones that regulate many essential functions in the body. 21-hydroxylase plays a role in producing hormones called [[cortisol]] and [[aldosterone]]. [[Cortisol]] helps maintain blood sugar levels, protects the body from [[stress]], and suppresses [[inflammation]]. Aldosterone is sometimes called the salt-retaining hormone because it regulates the amount of salt retained by the kidneys. The retention of salt affects fluid levels in the body and blood pressure. ==Notable studies == == Learn more == * [https://ghr.nlm.nih.gov/gene/CYP21A2 CYP21A2] - Genetics Home Reference ==See also == *[[Hormone]] *[[Sodium]] * [[:Category:Genes|Genes (category)]] ==References == {{Reflist}} [[Category:Genes]] [[Category:Diagnoses]]
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Templates used on this page:
Template:Cite web
(
edit
)
Template:Main other
(
edit
)
Template:Reflist
(
edit
)
Module:Check for unknown parameters
(
edit
)
Module:Citation/CS1
(
edit
)
Module:Citation/CS1/COinS
(
edit
)
Module:Citation/CS1/Configuration
(
edit
)
Module:Citation/CS1/Date validation
(
edit
)
Module:Citation/CS1/Identifiers
(
edit
)
Module:Citation/CS1/Utilities
(
edit
)
Module:Citation/CS1/Whitelist
(
edit
)
Module:No globals
(
edit
)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs