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CycloME
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==Cyclophosphamide== [[Cyclophosphamide]], a chemotherapy and immunosuppressant drug, has been investigated as a treatment in ME/CFS.<ref name="PhaseII">{{Cite web | title = Cyclophosphamide in Myalgic Encephalopathy/ Chronic Fatigue Syndrome (ME/CFS). Part A: an Open Label Phase-II Study With Six Intravenous Cyclophosphamide Infusions Four Weeks Apart, and Follow-up for 12 Months | date = 2021-05-10 | url = https://clinicaltrials.gov/ct2/show/NCT02444091 | last = Haukeland University Hospital|others=The Kavli Foundation, Oslo University Hospital}}</ref><ref name="Rekeland2020" /> As with the [[rituximab]] studies, the potential efficacy with ME was stumbled on by accident after treating two breast cancer patients, who also had ME, with cyclophosphamide, and having the women report that their ME symptoms improved. Before treatment, a bedbound ME patient walked an average of 326 steps per day. After six infusions with [[cyclophosphamide]], she was able to walk 13,000 steps daily.<ref name="mystery" />
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