Coxsackievirus B4
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Coxsackievirus B4 is an enterovirus that belong to the Picornaviridae family.
Coxsackievirus B4 has a cell tropism for natural killer cells and pancreatic islet cells
Type 1 Diabetes
Several studies have suggested a relationship between Coxsackie B4 and the onset of Type 1 diabetes.[1][2][3]
A study of patients with Type 1 Diabetes found that Coxsackie B4 was found to infect β cells and cause inflammation mediated by natural killer cells.[4]