Coxsackievirus B3
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In mouse models, Ampligen was found to be protective of Coxsackie B3-induced myocarditis.[1]
Selenium deficiency increases the virulence of Coxsackie B3 infections in a mouse model.[2]
Coxsackievirus B3 cleaves Mitochondrial Antiviral Signaling (MAVS) protein to inhibit type I interferon induction.[3] Conversely, upregulation of MAVS inhibits coxsackie B3 by increasing type-1 interferon production.[4]