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==== Infection and Ehlers-Danlos Syndromes ==== [[Ehlers-Danlos syndrome|Ehlers-Danlos Syndromes]] are a group connective tissue disorders caused by genetic defects in the production of collagen. Type III, [[hypermobile EDS]] (hEDS), is also thought to be genetic but as a genetic marker has not yet been identified; it is diagnosed via signs and symptoms. A 2018 case study of a patient who met the diagnostic criteria for hEDS and had a chronic Bartonella infection found their hEDS symptoms resolved with antibiotic treatment for Bartonella.<ref name=":0">{{Cite journal | last = Mozayeni|first = Bobak Robert | last2 = Maggi | first2 = Ricardo Guillermo | last3 = Bradley | first3 = Julie Meredith | last4 = Breitschwerdt | first4 = Edward Bealmear | date = Apr 2018 | title = Rheumatological presentation of Bartonella koehlerae and Bartonella henselae bacteremias |url =https://journals.lww.com/md-journal/Pages/articleviewer.aspx?year=2018&issue=04270&article=00032&type=Fulltext | journal = Medicine|language=en-US|volume=97 | issue = 17| pages = e0465|doi=10.1097/MD.0000000000010465|issn=0025-7974}}</ref> [[Mycoplasma pneumoniae]] has been associated with mitral valve degeneration, a complication of EDS.<ref>{{Cite journal | last = Tiveron | first = Marcos Gradim | last2 = Pomerantzeff | first2 = Pablo Maria Alberto | last3 = de Lourdes Higuchi | first3 = Maria | last4 = Reis | first4 = Marcia Martins | last5 = de Jesus Pereira | first5 = Jaqueline | last6 = Kawakami | first6 = Joyce Tieko | last7 = Ikegami | first7 = Renata Nishiyama | last8 = de Almeida Brandao | first8 = Carlos Manuel | last9 = Jatene | first9 = Fabio Biscegli | date = 2017-04-21 | title = Infectious agents is a risk factor for myxomatous mitral valve degeneration: A case control study | url = https://www.ncbi.nlm.nih.gov/pubmed/28431520 | journal = BMC infectious diseases|volume=17 | issue = 1 | pages = 297|doi=10.1186/s12879-017-2387-8|issn=1471-2334|pmc=5399830|pmid=28431520}}</ref>
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