Co-conditioning theory

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

The co-conditioning theory of ME/CFS was first proposed in 2010 and is biopsychosocial-based theory.[1] Co-conditioning is proposed to cause chronic fatigue syndrome as follows: "after repetitive overwork and/or stress, alarm signal to rest and fatigue sensation may cause in response to an unconditioned stimulus (impaired homeostasis and function) that has been paired with a conditioned stimulus (overwork and/or stress)".[1]

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A re-co-conditioning treatment is proposed, including cognitive behavioral therapy for "stress, stress responses, overwork, inactivity, and the psychological responses as a result of the familial, social, economic, and educational handicaps" combined with medication to reduce symptoms and restore homeostasis.[1]

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