Christopher Snell

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Source:Workwell

Christopher Ronald Snell, PhD, is the Scientific Director of Workwell Foundation, Ripon, California. He directs the Pacific Fatigue Lab at the Department of Health, Exercise, and Sport Sciences, at the University of the Pacific, Stockton, California, USA.[1]

IOM Committee on Diagnostic Criteria for ME/CFS[edit | edit source]

Dr Snell was a reviewer for the 2015 report produced by the Institute of Medicine's Committee on Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.[2]

Chronic Fatigue Syndrome Advisory Committee[edit | edit source]

Dr. Snell was Chair of the Health and Human Services's Chronic Fatigue Syndrome Advisory Committee committee from 04/01/07-04/01/11.[3]

Open letter to The Lancet[edit | edit source]

Two open letters to the editor of The Lancet urged the editor to commission a fully independent review of the PACE trial, which the journal had published in 2011. In 2016, Dr. Snell, along with 41 colleagues in the ME/CFS field, signed the second letter.

ME/CFS Common Data Element (CDE) Project[edit | edit source]

Member of the Quality of Life/Functional Status (CPET)/Activity Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke and the Centers for Disease Control and Prevention.[4]

Notable studies[edit | edit source]

  • 2001, Assessment of Functional Impairment by Cardiopulmonary Exercise Testing in Patients with Chronic Fatigue Syndrome[5] ABSTRACT
  • 2001, Chronic Fatigue Syndrome, Ampligen, and Quality of Life: A Phenomenological Perspective[6] ABSTRACT
  • 2002, Physical performance and prediction of 2-5A synthetase/RNase L antiviral pathway activity in patients with chronic fatigue syndrome[7] ABSTRACT
  • 2003, Subclassifying chronic fatigue syndrome through exercise testing[8] ABSTRACT
  • 2004, Immunologic Aspects of Chronic Fatigue Syndrome: Report on a Research Symposium Convened by The CFIDS Association of America and Co-Sponsored by the US Centers for Disease Control and Prevention and the National Institutes of Health[9] ABSTRACT
  • 2005, Exercise capacity and immune function in male and female patients with chronic fatigue syndrome (CFS)[10] FULL TEXT
  • 2007, Legal and Scientific Considerations of the Exercise Stress Test[11] ABSTRACT
  • 2007, Diminished Cardiopulmonary Capacity During Post-Exertional Malaise[12] ABSTRACT
  • 2010, Post-exertional malaise in women with chronic fatigue syndrome[13] ABSTRACT
  • 2010, Conceptual model for physical therapist management of chronic fatigue syndrome/myalgic encephalomyelitis[14] ABSTRACTFULL TEXT
  • 2011, Reliability and validity of Short Form 36 Version 2 to measure health perceptions in a sub-group of individuals with fatigue[15] ABSTRACT
  • 2011, Diagnostic accuracy of symptoms characterising chronic fatigue syndrome[16] ABSTRACT
  • 2012, Minimum data elements for research reports on CFS[17] FULL TEXT
  • 2013, Discriminative Validity of Metabolic and Workload Measurements for Identifying People With Chronic Fatigue Syndrome[18] FULL TEXT

Talks and interviews[edit | edit source]

  • 2011, National Institutes of Health (NIH) State of the Knowledge Workshop regarding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Research presenter
Cardiopulmulmonary Exercise Testing to Assess fatigue in ME/CFS (presentation starts at the 8:02:00 time marker)[19]

Learn more[edit | edit source]

See Also[edit | edit source]

References[edit | edit source]

  1. ↑ https://www.researchgate.net/profile/Christopher_Snell-UOP
  2. ↑ https://www.nap.edu/resource/19012/MECFS_Powerpoint.pdf
  3. ↑ http://nih.granicus.com/DocumentViewer.php?file=nih_e174f9bd-ae0f-4a45-9955-827cb608db2f.pdf
  4. ↑ https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?%2fnindscdereports%2fRoster&rs%3aCommand=Render&rc:Parameters=false&diseaseid=MECFS&custom:disableExcel=true&custom:disableXML=true&custom:disableCSV=true
  5. ↑ VanNess, J Mark; Snell, Christopher R; Fredrickson, Dean M.; Strayer, David R.; Stevens, Staci R (2001), "Assessment of Functional Impairment by Cardiopulmonary Exercise Testing in Patients with Chronic Fatigue Syndrome", Journal of Chronic Fatigue Syndrome, 8 (3–4): 103-109, doi:10.1300/J092v08n03_09
  6. ↑ Snell, Christopher R; Stevens, Staci R; VanNess, J Mark (2001), "Chronic Fatigue Syndrome, Ampligen, and Quality of Life: A Phenomenological Perspective", Journal of Chronic Fatigue Syndrome, 8 (3–4): 117-121, doi:10.1300/J092v08n03_11
  7. ↑ Snell, Christopher R; VanNess, J Mark; Strayer, David R.; Stevens, Staci R (2002), "Physical performance and prediction of 2-5A synthetase/RNase L antiviral pathway activity in patients with chronic fatigue syndrome", In Vivo, 16 (2): 107-9, PMID 12073768
  8. ↑ VanNess, J Mark; Snell, Christopher R; Strayer, David R.; Dempsey, IV, Line; Stevens, Staci R (2003), "Subclassifying chronic fatigue syndrome through exercise testing", Med Sci Sports Exerc, 35 (6): 908-13, doi:10.1249/01.MSS.0000069510.58763.E8, PMID 12783037
  9. ↑ Gerrity, T.R.; Papanicolaou, D.A.; Amsterdam, J.D.; Bingham, S.; Grossman, A.; Hedrick, T.; Herberman, R.B.; Krueger, G.; Levine, S.; Mohagheghpour, N.; Moore, R.C.; Oleske, J.M.; Snell, C.R.; CFIDS Association of America (2004), "Immunologic Aspects of Chronic Fatigue Syndrome: Report on a Research Symposium Convened by The CFIDS Association of America and Co-Sponsored by the US Centers for Disease Control and Prevention and the National Institutes of Health", Neuroimmunomodulation, 11: 351–357, doi:10.1159/000080144, PMID 15467349
  10. ↑ Snell, Christopher R; VanNess, J Mark; Strayer, David R.; Stevens, Staci R (2005), "Exercise capacity and immune function in male and female patients with chronic fatigue syndrome (CFS)", In Vivo, 19 (2): 387-90, PMID 15796202
  11. ↑ Ciccolella, Margaret; Stevens, Staci R.; Snell, Christopher R.; Vanness, J. Mark (2007), "Legal and Scientific Considerations of the Exercise Stress Test", Journal of Chronic Fatigue Syndrome, 14 (2): 61-75, doi:10.1300/J092v14n02_06
  12. ↑ VanNess, J Mark; Snell, Christopher R; Stevens, Staci R (2007), "Diminished Cardiopulmonary Capacity During Post-Exertional Malaise", Journal of Chronic Fatigue Syndrome, 14 (2): 77-85, doi:10.1300/J092v14n02_07
  13. ↑ VanNess, J Mark; Stevens, Staci R; Bateman, Lucinda; Stiles, Travis L; Snell, Christopher R (January 4, 2010), "Post-exertional malaise in women with chronic fatigue syndrome", J Womens Health (Larchmt), 2010 Feb, 19 (2): 239-44, doi:10.1089/jwh.2009.1507, PMID 20095909
  14. ↑ Davenport, Todd E.; Stevens, Staci R.; Snell, Christopher R.; Little, Tamara (2010), "Conceptual Model for Physical Therapist Management of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis", Physical Therapy, 90 (4): 602–614, doi:10.2522/ptj.20090047, PMID 20185614
  15. ↑ Davenport, Todd E.; Stevens, Staci R.; Baroni, K; Vanness, J. Mark; Snell, Christopher R. (2011), "Reliability and validity of Short Form 36 Version 2 to measure health perceptions in a sub-group of individuals with fatigue", Disabil Rehabil, 33 (25–26): 2596-604, doi:10.3109/09638288.2011.582925, PMID 21682669
  16. ↑ Davenport, Todd E.; Stevens, Staci R.; Baroni, Katie; Vanness, J. Mark; Snell, Christopher R. (2011), "Diagnostic accuracy of symptoms characterizing chronic fatigue syndrome", Disabil Rehabil, 33 (19–20): 1768-75, doi:10.3109/09638288.2010.546936, PMID 21208154
  17. ↑ Jason, LA; Unger, ER; Dimitrakoff, JD; Fagin, AP; Houghton, M; Cook, DB; Marshall, GD, Jr; Klimas, N; Snell, C (2012), "Minimum data elements for research reports on CFS", Brain, Behavior, Immunology, 26 (3): 401-6, doi:10.1016/j.bbi.2012.01.014, PMID 22306456
  18. ↑ Snell, Christopher R; Stevens, Staci R; Davenport, Todd E.; VanNess, J Mark (2013), "Discriminative Validity of Metabolic and Workload Measurements for Identifying People With Chronic Fatigue Syndrome", Physical Therapy, 93 (11): 1484–1492, doi:10.2522/ptj.20110368
  19. ↑ http://www.pacific.edu/Academics/Schools-and-Colleges/College-of-the-Pacific/Academics/Departments-and-Programs/Archives.html

National Academy of Medicine (NAM) - An American non-profit, non-governmental organization which provides expert advice to governmental agencies on issues relating to biomedical science, medicine and health. Formerly known as the Institute of Medicine (IOM).

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

two-day cardiopulmonary exercise test (CPET) - A diagnostic test which involves testing an ME/CFS patient exercising on an exercise machine, while monitoring their respiration, especially oxygen consumption. This test is repeated the following day in order to confirm the patient's inability to replicate the first-day performance. This test is thought to be the most objective way to detect post-exertional malaise.

stress Stress can by either physical or psychological, or both. Stress is either 1) a state of emotional or psychological strain or 2) the physical stress (pressure or tension) that a physical object such the human body is placed under, e.g., a stress test is a medical test that monitors the cardiovascular system during strenuous exercise.

accuracy The "closeness of an observation to the true clinical state". With respect to diagnostic tests, "accuracy" means how specific and sensitive the test is.

National Institutes of Health (NIH) - A set of biomedical research institutes operated by the U.S. government, under the auspices of the Department of Health and Human Services.

Chronic Fatigue and Immune Dysfunction Syndrome (CFIDS) - Chronic Fatigue and Immune Dysfunction Syndrome is another term for Chronic Fatigue Syndrome, but one which emphasizes the immunological aspects of the disease. Popular in the 1990s, this term has apparently fallen into disuse.

Centers for Disease Control and Prevention (CDC) - The Centers for Disease Control and Prevention is a U.S. government agency dedicated to epidemiology and public health. It operates under the auspices of the Department of Health and Human Services.

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