Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Chlamydia pneumoniae
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
'''''Chlamydia pneumoniae''''' (also referred to as '''Chlamydophila pneumoniae''' or '''CPN''') is an intracellular bacterium of the species ''Chlamydophila'', and can infect people via airborne transmission. It is a major cause of community-acquired [[pneumonia]].<ref>[https://www.mc.vanderbilt.edu/reporter/index.html?ID=779 ''Chlamydia pneumoniae'' not caught like you thought]</ref> It has been implicated as a potential cause of [[ME/CFS]] in a subset of patients. A study by [[John Chia|Chia & Chia]] found that 10% of their patients had a ''chlamydophila pneumoniae'' infection which may have caused or contributed to their ME/CFS.<ref name="Chia">{{Cite journal | last = Chia | first = J.K. | authorlink = John Chia | last2 = Chia | first2 = L.Y. | author-link2 = Laura Chia | date = Aug 1999 | title = Chronic Chlamydia pneumoniae infection: a treatable cause of chronic fatigue syndrome | url =https://www.ncbi.nlm.nih.gov/pubmed/10476765 | journal = [[Clinical Infectious Diseases]] | volume = 29 | issue = 2 | pages = 452β453|doi=10.1086/520239|issn=1058-4838|pmid=10476765|quote=|via=|pmc=|access-date=}}</ref> A chronic ''chlamydophila pneumoniae'' infection can be treated with [[antibiotics]].<ref>{{Cite journal | last = Tovey|first = John E. | date = Oct 2007 | title = Chlamydia pneumoniae infection a treatable cause of Chronic Fatigue Syndrome | url =https://www.bmj.com/rapid-response/2011/11/01/chlamydia-pneumoniae-infection-treatable-cause-chronic-fatigue-syndrome | journal = [[BMJ]]|language=en}}</ref> ==Testing== Accurately testing for ''chlamydia pneumoniae'' can be difficult, therefore, a negative blood test may not mean you do not have an infection. Additionally, there is a general shortage worldwide of facilities which can identify/diagnose ''Chlamydia pneumoniae''.<ref>{{Cite web | url = http://cpnhelp.org/diagnosis_issues | title = Diagnosis Issues {{!}} Cpnhelp.org | website = cpnhelp.org|access-date=2020-01-28}}</ref> Common tests for ''chlamydophila pneumoniae'' include the [[Microimmunofluorescence test|microimmunofluorescence]] (MIF) test<ref>{{Cite journal | last = Wang|first = San-pin | authorlink = | date = Jun 2000 | title = The Microimmunofluorescence Test for Chlamydia pneumoniae Infection: Technique and Interpretation | url =https://academic.oup.com/jid/article/181/Supplement_3/S421/2191092?searchresult=1 | journal = The Journal of Infectious Diseases|language=en | volume = 181 | issue = Supplement 3| pages=S421βS425|doi=10.1086/315622|pmc=|pmid=|access-date=|quote=|via=}}</ref> or via biopsy. Dr. John Chia notes that most ME/CFS patients with active Chlamydia pneumoniae infection will have high IgG antibody levels (but IgM is negative). Dr. Chia has treated patients with titers as low as 1:128.<ref>{{Cite web | url = https://academic.oup.com/cid/article-pdf/29/2/452/768183/29-2-452.pdf | title=Chronic Chlamydia pneumoniae Infection: A Treatable Cause of Chronic Fatigue Syndrome | last = Chia | first = John | authorlink = | date = August 29, 1999 | website = | archive-url = | archive-date = |url-status = | access-date=}}</ref> ==Treatment== A ''chlamydophila pneumoniae'' infection, while an uncommon cause of ME/CFS, is one of the more treatable forms. Antibiotic treatment with [[azithromycin]] or [[rifampin]] can therefore improve or even cure patients. Chia & Chia found that while antibiotic treatment was successful in many patients, relapse was also common.<ref name="Chia" /> Some patients have reported recovery after being treated with Dr Stratton's original protocol<ref>{{Cite web | url = http://cpnhelp.org/astrodianas_story_cure_fr | title = Astrodiana's story: Cure from Chronic Fatigue Syndrome with Dr. Stratton's original protocol {{!}} Cpnhelp.org | website = cpnhelp.org|access-date=2020-01-28}}</ref>. More information on treatment options can be found on CPN Help's Treatment Protocols page<ref>{{Cite web | url = http://cpnhelp.org/treatment_protocols | title = Treatment Protocols {{!}} Cpnhelp.org | website = cpnhelp.org|access-date=2020-01-28}}</ref>. == Notable studies == *1999, Chronic ''Chlamydia pneumoniae'' Infection: A Treatable Cause of Chronic Fatigue Syndrome<ref name="Chia" /> - ([https://academic.oup.com/cid/article/29/2/452/274438 Article]) *2003, Multiple co-infections (Mycoplasma, Chlamydia, human herpes virus-6) in blood of chronic fatigue syndrome patients: association with signs and symptoms<ref>{{Cite journal | last = Nicolson | first = G.L. | last2 = Gan | first2 = R. | last3 = Haier | first3 = J. | date = May 2003 | title = Multiple co-infections (Mycoplasma, Chlamydia, human herpes virus-6) in blood of chronic fatigue syndrome patients: association with signs and symptoms |url =https://pubmed.ncbi.nlm.nih.gov/12887507/ | journal = APMIS: acta pathologica, microbiologica, et immunologica Scandinavica | volume = 111 | issue = 5 | pages = 557β566|doi=10.1034/j.1600-0463.2003.1110504.x|issn=0903-4641|pmid=12887507|pmc=|quote= | authorlink = Garth Nicolson | author-link2 = |access-date=|via=}}</ref> - ([https://pubmed.ncbi.nlm.nih.gov/12887507/ Abstract]) ==Learn more== *[http://www.cpnhelp.org/ CPN Help Website] *John E. Tovey: [http://www.bmj.com/rapid-response/2011/11/01/chlamydia-pneumoniae-infection-treatable-cause-chronic-fatigue-syndrome ''Chlamydia pneumoniae'' infection a treatable cause of Chronic Fatigue Syndrome: Response (BMJ)] == References == {{reflist}} [[Category:Bacteria]] [[Category:Infectious agents]] [[Category:Triggers and risk factors]]
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Templates used on this page:
Template:Cite journal
(
edit
)
Template:Cite web
(
edit
)
Template:Main other
(
edit
)
Template:Reflist
(
edit
)
Module:Check for unknown parameters
(
edit
)
Module:Citation/CS1
(
edit
)
Module:Citation/CS1/COinS
(
edit
)
Module:Citation/CS1/Configuration
(
edit
)
Module:Citation/CS1/Date validation
(
edit
)
Module:Citation/CS1/Identifiers
(
edit
)
Module:Citation/CS1/Utilities
(
edit
)
Module:Citation/CS1/Whitelist
(
edit
)
Module:No globals
(
edit
)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs