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Chemical sensitivities
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{{stub}} '''Chemical sensitivities''' refers to symptoms are being experienced in response to exposure to certain chemicals, which would not trigger adverse symptoms for most people, at least at low concentrations.<ref name="features">"1.3 Clinical features of the disease". ''The Italian Consensus on Multiple Chemical Sensitivity (MCS) -- Consensus Document and Guidelines on Multiple Chemical Sensitivity (MCS).'' The Italian Workgroup on MCS. Published 23 May 2019. University of Milan, Italy.</ref> Common triggers for chemical sensitivities include pesticides, perfume and petrochemicals, like petrol and paint.<ref name="features">"1.3 Clinical features of the disease". ''The Italian Consensus on Multiple Chemical Sensitivity (MCS) -- Consensus Document and Guidelines on Multiple Chemical Sensitivity (MCS).'' The Italian Workgroup on MCS. Published 23 May 2019. University of Milan, Italy.</ref> Natural irritants like mold and wood-fire smoke are also common triggers.<ref name="triggering">"1.2 Triggering of MCS", ''The Italian Consensus on Multiple Chemical Sensitivity (MCS) -- Consensus Document and Guidelines on Multiple Chemical Sensitivity (MCS).'' The Italian Workgroup on MCS. Published 23 May 2019. University of Milan, Italy.</ref><ref name="Rossi2017">Rossi, S; Pitidis, A (2017). "Multiple Chemical Sensitivity: Review of the State of the Art in Epidemiology, Diagnosis, and Future Perspectives". Journal of Occupational and Environmental Medicine. 60 (2): 138–146. doi:10.1097/JOM.0000000000001215. PMC5794238. <nowiki>PMID 29111991</nowiki>. </ref> Symptoms of chemical sensitivities can include: headache, migraine, cognitive impairment, dizziness, fatigue, nausea, vomiting, cardiac abnormalities, skin rashes, asthma, and anaphylaxis.<ref name="features">"1.3 Clinical features of the disease". ''The Italian Consensus on Multiple Chemical Sensitivity (MCS) -- Consensus Document and Guidelines on Multiple Chemical Sensitivity (MCS).'' The Italian Workgroup on MCS. Published 23 May 2019. University of Milan, Italy.</ref><ref name="triggering">"1.2 Triggering of MCS", ''The Italian Consensus on Multiple Chemical Sensitivity (MCS) -- Consensus Document and Guidelines on Multiple Chemical Sensitivity (MCS).'' The Italian Workgroup on MCS. Published 23 May 2019. University of Milan, Italy.</ref><ref name="Aus2010">''A Scientific Review of Multiple Chemical Sensitivity: Identifying Key Research Needs.'' Published in 2010 by the National Industrial Chemicals Notification and Assessment Scheme, Australian Government. Canberra, Australia <nowiki>http://test.nicnas.gov.au/Media/Latest_News/MCS.asp</nowiki></ref><ref name="Valderrama2016">Valderrama Rodríguez M, Revilla López MC, Blas Diez MP, Vázquez Fernández del Pozo S, Martín Sánchez JI. ''Review of the scientific evidence on Multiple Chemical Sensitivity''. Spanish Ministry of health, social services and equality. The Aragon Institute of Health Sciences, Spain; 2015. p.31</ref><ref name="Genuis2013">{{cite journal | last1 = Genuis | first1 = SJ | date = May 2013 | title = Chemical sensitivity: pathophysiology or pathopsychology? | journal = Clinical Therapeutics|type=Review | volume = 35 | issue = 5 | pages = 572–7|doi=10.1016/j.clinthera.2013.04.003|pmid=23642291}}</ref><ref name="Ross1999">{{cite journal|vauthors=Ross PM, Whysner J, Covello VT, Kuschner M, Rifkind AB, Sedler MJ, Trichopoulos D, Williams GM| year = 1999 | title = Olfaction and Symptoms in the Multiple Chemical Sensitivities Syndrome | url = | journal = Preventive Medicine | volume = 28 | issue = 5 | pages = 467–480|doi=10.1006/pmed.1998.0469|pmid=10329337}}</ref><ref name="Graveling1999">{{cite journal|vauthors=Graveling RA, Pilkington A, George JP, Butler MP, Tannahill SN| year = 1999 | title = A review of multiple chemical sensitivity | url = | journal = Occupational and Environmental Medicine | volume = 56 | issue = 2 | pages = 73–85|doi=10.1136/oem.56.2.73|pmc=1757696|pmid=10448311}}</ref> New chemical sensitivities are recognized as a common symptom of ME/CFS,<ref name="ICC2011criteria"/><ref name="canadianconsensus-CCC">{{Citation | last1 = Carruthers | first1 = Bruce M. | author-link1 = Bruce Carruthers | last2 = Jain | first2 = Anil Kumar | author-link2 = Anil Kumar Jain | last3 = De Meirleir | first3 = Kenny L. | author-link3 = Kenny De Meirleir | last4 = Peterson | first4 = Daniel L. | author-link4 = Daniel Peterson | last5 = Klimas | first5 = Nancy G. | author-link5 = Nancy Klimas | last6 = Lerner | first6 = A. Martin | author-link6 = Martin Lerner | last7 = Bested | first7 = Alison C. | author-link8 = Alison Bested | last8 =Flor-Henry | first8 = Pierre | author-link8 = Pierre Flor-Henry | last9 = Joshi | first9 = Pradip | author-link9 = Pradip Joshi | last10 = Powles | first10 = AC Peter | author-link10 = A C Peter Powles | last11 = Sherkey | first11 = Jeffrey A. | author-link11 = Jeffrey Sherkey | last12 = van de Sande | first12 = Marjorie I. | author-link12 = Marjorie van de Sande | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols| journal = Journal of Chronic Fatigue Syndrome | volume = 11 | issue = 2 | pages = 7-115 | date = 2003 | pmid = | doi = 10.1300/J092v11n01_02| url = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf}}</ref><ref name="AMMES">{{Cite web | url = https://ammes.org/overlapping-conditions/ | title = Overlapping Conditions | website = [[American ME and CFS Society]]|language=en-US|access-date=2018-08-12}}</ref> and some people react to so many substances that they also meet the diagnostic criteria for [[Multiple chemical sensitivity|Multiple Chemical Sensitivity]] (MCS).<ref name="canadianconsensus-CCC"/><ref name="pmid10444033">{{cite journal| year = 1999 | title = Multiple chemical sensitivity: a 1999 consensus | journal = Arch. Environ. Health | volume = 54 | issue = 3 | pages = 147–9|doi=10.1080/00039899909602251|pmid=10444033 | url = https://semanticscholar.org/paper/5d389fb8a204e089ce22e9cc7720aa8507581c2f}}</ref><ref name="features">"1.3 Clinical features of the disease". ''The Italian Consensus on Multiple Chemical Sensitivity (MCS) -- Consensus Document and Guidelines on Multiple Chemical Sensitivity (MCS).'' The Italian Workgroup on MCS. Published 23 May 2019. University of Milan, Italy.</ref> ==Symptom recognition== *The [[International Consensus Criteria]] lists sensitivities to food, medications, odors or chemicals as an optional criteria for diagnosis, under the section ''C. Immune, gastro-intestinal and genitourinary Impairments''.<ref name="ICC2011criteria" /> *2018, The [[Centers for Disease Control and Prevention]] note ME/CFS patients can have "allergies and sensitivities to foods, odors, chemicals, or noise."<ref name="CDC-symptoms">{{Cite web | title = Symptoms {{!}} Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | url = https://www.cdc.gov/me-cfs/symptoms-diagnosis/symptoms.html | website = [[Centers for Disease Control and Prevention]] | date = 2018-05-18|access-date=2018-08-23|language=en-us}}</ref> * The [[Canadian Consensus Criteria]] for ME/CFS (2003) includes "new sensitivities to food, medications and/or chemicals" asan optional immune system symptom of ME/CFS. ==See also== *[[New allergies and intolerances]] *[[Multiple chemical sensitivity]] ==References== <references> <ref name="ICC2011criteria">{{citation | last =Carruthers | first1 = BM | author-link1 = Bruce Carruthers | last2 =van de Sande | first2 = MI | author-link2 = Marjorie van de Sande | last3 = De Meirleir | first3 = KL | author-link3 = Kenny de Meirleir | last4 = Klimas | first4 = NG | author-link4 = Nancy Klimas | last5 = Broderick | first5 = G | author-link5 = Gordon Broderick | last6 = Mitchell | first6 = T | author-link6 = Terry Mitchell | last7 = Staines | first7 = D | author-link8 = Donald Staines | last8 =Powles | first8 = ACP | author-link8 = A C Peter Powles | last9 = Speight | first9 = N | author-link9 = Nigel Speight | last10 = Vallings | first10 = R | author-link10 = Rosamund Vallings | last11 = Bateman | first11 = L | author-link11 = Lucinda Bateman | last12 = Baumgarten-Austrheim | first12 = B | author-link12 = Barbara Baumgarten-Austrheim | last13 = Bell | first13 = DS | author-link13 = David Bell | last14 = Carlo-Stella | first14 = N | author-link14 = Nicoletta Carlo-Stella | last15 = Chia | first15 = J | author-link15 = John Chia | last16 = Darragh | first16 = A | author-link16 = Austin Darragh | last17 = Jo | first17 = D | author-link17 = Daehyun Jo | last18 = Lewis | first18 = DP | author-link18 = Donald P Lewis | last19 = Light | first19 = AR | author-link19 = Alan Light | last20 = Marshall-Gradisnik | first20 = S | author-link20 = Sonya Marshall-Gradisnik | last21 = Mena | first21 = I | author-link21 = Ismael Mena | last22 = Mikovits | first22 = JA | author-link22 = Judy Mikovits | last23 = Miwa | first23 = K | author-link23 = Kunihisa Miwa | last24 = Murovska | first24 = M | author-link24 = Modra Murovska | last25 = Pall | first25 = ML | author-link25= Martin Pall | last26 = Stevens | first26 = SR | author-link26 = Staci Stevens | title = Myalgic encephalomyelitis: International Consensus Criteria | journal = Journal of Internal Medicine | volume = 270 | issue = 4 | pages = 327–338 | date = August 22, 2011 | pmid = 21777306 | doi = 10.1111/j.1365-2796.2011.02428.x | url = http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2796.2011.02428.x/full }}</ref> </references> [[Category:Signs and symptoms]] [[Category:Sensitivity signs and symptoms]] [[Category:Allergy signs and symptoms]] [[Category:Immune signs and symptoms]]
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