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Channelopathy hypothesis
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[[Abhijit Chaudhuri]] and [[Peter Behan]] proposed that [[myalgic encephalomyelitis]]/[[chronic fatigue syndrome]] was an acquired neurological channelopathy illness, meaning that the symptoms are the result of [[ion transportation |ion channel transportation]] problems affecting the body's [[nervous system]]. The [[channelopathy]] hypothosis was first published in 1999. ==Theory== ==Evidence== [[Ion transportation]] symptoms are recognized in the diagnostic criteria of the [[International Consensus Criteria]]. == Notable studies == * 1999, Chronic fatigue syndrome is an acquired neurological channelopathy<ref>{{Cite journal | last = Chaudhuri | first = Abhijit | authorlink = | last2 = Behan | first2 = Peter O. | date = 1999-01-01 | title = Chronic fatigue syndrome is an acquired neurological channelopathy | url = http://booksc.xyz/book/89608/262397 | journal = Human Psychopharmacology: Clinical and Experimental|language=en | volume = 14 | issue = 1 | pages = |doi=10.1002/(sici)1099-1077(199901)14:1|issn=1099-1077|quote=|via=}}</ref> * 2000, The symptoms of chronic fatigue syndrome are related to abnormal ion channel function<ref>{{Cite journal | last = Chaudhuri | first = A. | authorlink = Abhijit Chaudhuri | last2 = Watson | first2 = W.S. | last3 = Pearn | first3 = J. | last4 = Behan | first4 = P.O. | author-link4 = Peter Behan | date = Jan 2000 | title = The symptoms of chronic fatigue syndrome are related to abnormal ion channel function | url =http://www.alfredblasi.net/documentacio/es_eng_symptonsareiondisorder.pdf | journal=Medical Hypotheses | volume = 54 | issue = 1 | pages = 59β63|doi=10.1054/mehy.1998.0822|issn=0306-9877|quote=|via= | author-link2 = Walter Watson | author-link3 = Jo Pearn}}</ref> * 2003, Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome: Preliminary Observations<ref>{{Cite journal | last = Nijs | first = Jo | authorlink = Jo Nijs | last2 = De Becker | first2 = Pascale | author-link2 = Pascale De Becker | last3 = Demanet | first3 = Christian | author-link3 = Christian Demanet | last4 = McGregor | first4 = Neil R. | author-link4 = Neil McGregor | last5 = Englebienne | first5 = Patrick | author-link5 = Patrick Englebienne | last6 = Verhas | first6 = Michel | author-link6 = Michel Verhas | last7 = De Meirleir | first7 = Kenny | author-link8 = Kenny De Meirleir | date = Jan 2003 | title = Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome | url =https://www.researchgate.net/profile/Christian_Demanet/publication/234841733_Monitoring_a_hypothetical_channelopathy_in_Chronic_Fatigue_Syndrome_preliminary_observations/links/0deec526e1c79ac883000000/Monitoring-a-hypothetical-channelopathy-in-Chronic-Fatigue-Syndrome-preliminary-observations.pdf | journal=Journal of Chronic Fatigue Syndrome|language=en | volume = 11 | issue = 1 | pages = 117β133|doi=10.1300/j092v11n01_03|issn=1057-3321|quote=|via=}}</ref>Β ==Treatment== ==See also== * [[Channelopathy]] * [[Ion transportation]] * [[Transient receptor potential melastatin 3]] (TRPM3) ==Learn more== ==References== {{Reflist}} [[Category:Channelopathy]] [[Category:Medical hypotheses]]
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