Carmen Scheibenbogen
Professor Doctor Carmen Scheibenbogen is an Internal Medicine physician, ME/CFS doctor and the Professor for Immunology and Deputy Chair, Institute of Medical Immunology, at the University Hospital Charité in Berlin, Germany. Her research focuses on the role of Epstein-Barr virus (EBV), particularly the characterization of EBV specific B cell and T cell response and the enhanced antibody response against EBV peptides in ME versus healthy controls.[1]
Diagnostic test[edit | edit source]
Professor Scheibenbogen helped create the CellTrend Diagnostic Test which may help identify a subset of 20-30% of all patients with ME/CFS. These patients have elevated levels of three auto-antibodies, i.e., against the b2-adrenergic receptor, against the muscarinic cholinergic receptor 3 (M3) and against the muscarinic cholinergic receptor 4 (M4).[2]
Awards[edit | edit source]
- 2017 - A team comprised of Dr. Carmen Scheibenbogen and Dr. Franziska Sotzny of Charité Universitätsmedizin Berlin were awarded a 2017 Ramsay Award grant from the Solve ME/CFS Initiative for researching immunometabolism of T cells and monocytes in ME/CFS.[3]
- 2016 Ramsay Award Program grant recipient, sponsored by the Solve ME/CFS Initiative for Autoimmune Signature in CFS/ME. This grant was shared with Madlen Löbel, Charité Universitätsmedizin Berlin.[4]
Notable studies[edit | edit source]
- 2018, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome – Evidence for an autoimmune disease[5] (Full Text)
- 2018, Immunoadsorption to remove ß2 adrenergic receptor antibodies in Chronic Fatigue Syndrome CFS/ME[6] (Full Text)
- 2017, The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE[7] (Full Text)
- 2016, Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome[8] (Full Text)
- 2015, Frequent IgG subclass and mannose binding lectin deficiency in patients with chronic fatigue syndrome[9] (Full Text)
- 2015, Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome[10] (Full Text)
- 2014, Deficient EBV-Specific B- and T-Cell Response in Patients with Chronic Fatigue Syndrome[11] (Full Text)
Clinic location[edit | edit source]
- Charité University Medicine, Berlin, Germany
Talks & interviews[edit | edit source]
- 2014, Speaker at the 9th Invest in ME International ME Conference DVD available
Online presence[edit | edit source]
- PubMed
- Institute for Medical Immunology
- Website
- YouTube
Learn more[edit | edit source]
- Institution
See also[edit | edit source]
References[edit | edit source]
- ↑ http://www.investinme.eu/IIMEC9.shtml#dvd
- ↑ http://www.celltrend.de/cfs-diagnostics.html
- ↑ http://solvecfs.org/2017-ramsay-award-program-results/
- ↑ http://solvecfs.org/2016-ramsay-award-program-results/
- ↑ Sotzny, Franziska; Blanco, Julià; Capelli, Enrica; Castro-Marrero, Jesús; Steiner, Sophie; Murovska, Modra; Scheibenbogen, Carmen (2018), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome – Evidence for an autoimmune disease", Autoimmunity Reviews, doi:10.1016/j.autrev.2018.01.009
- ↑ Scheibenbogen C, Loebel M, Freitag H, Krueger A, Bauer S, Antelmann M, et al. (2018) Immunoadsorption to remove ß2 adrenergic receptor antibodies in Chronic Fatigue Syndrome CFS/ME. PLoS ONE 13(3): e0193672. https://doi.org/10.1371/journal.pone.0193672
- ↑ Scheibenbogen, C., Freitag, H., Blanco, J., Capelli, E., Lacerda, E., Authier, J., … Murovska, M. (2017). The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE. Journal of Translational Medicine, 15, 162. http://doi.org/10.1186/s12967-017-1263-z
- ↑ Loebel, M; Grabowski, P; Heidecke, H; Bauer, S; Hanitsch, LG; Wittke, K; Meisel, C; Reinke, P; Volk, H; Fluge, Ø; Mella, O; Scheibenbogen, C (2016), "Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome", Brain, behavior, and immunity, 52: 32-39, doi:10.1016/j.bbi.2015.09.013
- ↑ Guenther, Sabrina; Loebel, Madlen; Mooslechner, Agnes A; Knops, Michael; Hanitsch, Leif G; Grabowski, Patricia; Wittke, Kirsten; Meisel, Christian; Unterwalder, Nadine; Volk, Hans-Dieter; Scheibenbogen, Carmen (2015), "Frequent IgG subclass and mannose binding lectin deficiency in patients with chronic fatigue syndrome", Human Immunology, 76 (10): 729-35, doi:10.1016/j.humimm.2015.09.028
- ↑ Loebel, Madlen; Mooslechner, Agnes Anna; Bauer, Sandra; Günther, Sabrina; Letsch, Anne; Hanitsch, Leif G; Grabowski, Patricia; Meisel, Christian; Volk, Hans-Dieter; Scheibenbogen, Carmen (2015), "Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome", Journal of Translational Medicine, 13, doi:10.1186/s12967-015-0628-4
- ↑ Loebel, Madlen; Strohschein, Kristin; Giannini, Carolin; Koelsch, Uwe; Bauer, Sandra; Doebis, Cornelia; Thomas, Sybill; Unterwalder, Nadine; von Baehr, Volker; Reinke, Petra; Knops, Michael; Hanitsch, Leif G.; Meisel, Christian; Volk, Hans-Dieter; Scheibenbogen, Carmen (January 15, 2014), "Deficient EBV-Specific B- and T-Cell Response in Patients with Chronic Fatigue Syndrome", PLoS One, doi:10.1371/journal.pone.0085387