Cardiovascular system
Numerous cardiac abnormalities have been documented in Myalgic Encephalomyelitis and Chronic Fatigue Syndrome patients.
These include smaller than normal left ventricle of the heart[1][2] and low cardiac output[3][4].
A 2016 study in the Netherlands was the first to use contrast-enhanced cardiac magnetic resonance (CMR) imaging in assessing cardiac involvement in women who have CFS. Twelve women were recruited from a specialised CFS centre who had a diagnosis of CFS based on the Fukuda criteria. Thirty-six age- and gender-matched controls, also, were included. The conclusions were that in patients with CFS, cardiac magnetic resonance demonstrated lower left ventricle dimensions and a mildly reduced left ventricle function. Heart wall motion abnormalities and the presence of myocardial fibrosis were observed in some CFS patients.[5]
Reduced cardiac volumes have been associated with blood volume, but not length of disease.[6]
A study found that blood volume is a strong physiological correlate of peak oxygen consumption in patients with CFS.[7]
Orthostatic intolerance is also common.[8]
CFS patients have several risk factors for heart disease.[9]
The mean age of death from heart failure of CFS patients is 58.7 years as compared to 83.1 years for the general population.[10]
Learn more[edit | edit source]
- 2016, Chronic fatigue syndrome in women assessed with combined cardiac magnetic resonance imaging
- 2016, The Blood Volume Paradox in ME/CFS and POTS
- 2016, Reduced cardiac volumes in chronic fatigue syndrome associate with plasma volume but not length of disease: a cohort study
- 2016, Chronic Fatigue Syndrome: the Small Heart Disease
- 2016, Getting to the heart of chronic fatigue syndrome
See also[edit | edit source]
References[edit | edit source]
- ↑ Miwa K., "Cardiac dysfunction and orthostatic intolerance in patients with myalgic encephalomyelitis and a small left ventricle" Heart Vessels, July 2015
- ↑ Hollingsworth K.G "Impaired cardiac function in chronic fatigue syndrome measured using magnetic resonance cardiac tagging" J Intern Med 2012; 271: 264–270.
- ↑ Miwa K., Fujita M., "Cardiovascular dysfunction with low cardiac output due to a small heart in patients with chronic fatigue syndrome" Intern Med, 2009;48(21):1849-54
- ↑ Miwa K, Fujita M., "Small Heart With Low Cardiac Output for Orthostatic Intolerance in Patients With Chronic Fatigue Syndrome" Clinical Cardiology, Volume 34, Issue 12, 2011
- ↑ Olimulder, M.A.G.M.; Galjee, M.A.; Wagenaar, L.J.; van Es, J.; van der Palen, J.; Visser, F. C.; Vermeulen, R.C.W.; von Birgelen, C. (2016), "Chronic fatigue syndrome in women assessed with combined cardiac magnetic resonance imaging", Netherlands Heart Journal, doi:10.1007/s12471-016-0885-8
- ↑ Reduced cardiac volumes in chronic fatigue syndrome associate with plasma volume but not length of disease: a cohort study
- ↑ Blood volume and its relation to peak O2consumption and physical activity in patients with chronic fatigue
- ↑ Gerwin Morris, Michael Maes, see citations 12 through 27 in "Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics" BMC Medicine, 17 September 2013
- ↑ Michael Maes, Frank N.M. Twisk, "Why myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may kill you: disorders in the inflammatory and oxidative and nitrosative stress (IO&NS) pathways may explain cardiovascular disorders in ME/CFS" Activitas Nervosa Superior Rediviva, 20 December 2009
- ↑ Jason LA, Corradi K, Gress S, Williams S, Torres-Harding S, "Causes of death among patients with chronic fatigue syndrome" Health Care Women Int., 27(7): 615-626. 2006