Cara Tomas

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Cara Tomas, PhD, is a Postdoctoral Research Associate at the Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK. Tomas' interest in ME/CFS stems from her own experience with acute onset ME/CFS leaving her bedbound for a time.[1]

Notable studies[edit | edit source]

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Online presence[edit | edit source]

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References[edit | edit source]

  1. ↑ 1.0 1.1 Streeten, David H.P.; Bell, David S. (January 1998). "Circulating Blood Volume in Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 4 (1): 3–11. doi:10.1300/j092v04n01_02. ISSN 1057-3321.
  2. ↑ Tomas, Cara; Brown, Audrey; Strassheim, Victoria; Elson, Joanna; Newton, Julia; Manning, Philip (October 24, 2017). "Cellular bioenergetics is impaired in patients with chronic fatigue syndrome". PLOS ONE. 12 (10): e0186802. doi:10.1371/journal.pone.0186802. ISSN 1932-6203. PMID 29065167.
  3. ↑ Tomas, Cara; Finkelmeyer, Andreas; Hodgson, Tim; MacLachlan, Laura; MacGowan, Guy A; Blamire, Andrew M; Newton, Julia L (2017), "Elevated brain natriuretic peptide levels in chronic fatigue syndrome associate with cardiac dysfunction: a case control study", Open Heart, doi:10.1136/openhrt-2017-000697
  4. ↑ Tomas, Cara; Newton, Julia L (2018), "Metabolic abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a mini-review", Biochemical Society Transactions, doi:10.1042/BST20170503, PMID 29666214
  5. ↑ Xu, Jiabao; Potter, Michelle; Tomas, Cara; Elson, Jo; Morten, Karl; Poulton, Joanna; Wang, Ning; Jin, Hanqing; Hou, Zhaoxu (2018). "A new approach to find biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) by single-cell Raman micro-spectroscopy". The Analyst. doi:10.1039/C8AN01437J. ISSN 0003-2654.
  6. ↑ Venter, Marianne; Tomas, Cara; Pienaar, Ilse S.; Strassheim, Victoria; Erasmus, Elardus; Ng, Wan-Fai; Howell, Neil; Newton, Julia L.; Van der Westhuizen, Francois H. (December 2019). "MtDNA population variation in Myalgic encephalomyelitis/Chronic fatigue syndrome in two populations: a study of mildly deleterious variants". Scientific Reports. 9 (1). doi:10.1038/s41598-019-39060-1. ISSN 2045-2322. PMID 30814539.
  7. ↑ Tomas, Cara; Elson, Joanna L (February 26, 2019). "The role of mitochondria in ME/CFS: a perspective". Fatigue: Biomedicine, Health & Behavior: 1–7. doi:10.1080/21641846.2019.1580855. ISSN 2164-1846.
  8. ↑ Tomas, Cara; Brown, Audrey E.; Newton, Julia L.; Elson, Joanna L. (March 1, 2019). "Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients using two cell types". PeerJ. 7: e6500. doi:10.7717/peerj.6500. ISSN 2167-8359. PMID 30847260.
  9. ↑ Morten, Karl J.; Newton, Julia L.; Elson, Joanna L.; Potter, Michelle; Lodge, Tiffany A.; Tomas, Cara (August 7, 2019). "Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test". Scientific Reports. 9 (1): 1–9. doi:10.1038/s41598-019-47966-z. ISSN 2045-2322.
  10. ↑ Tomas, Cara; Elson, Joanna L.; Newton, Julia L.; Strassheim, Victoria; Walker, Mark (April 10, 2020). "The effect of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) severity on cellular bioenergetic function". PLoS ONE. 15 (4): e0231136. doi:10.1371/journal.pone.0231136.
  11. ↑ Tomas, Cara; Elson, Joanna L.; Newton, Julia L.; Walker, Mark (December 2020). "Substrate utilisation of cultured skeletal muscle cells in patients with CFS". Scientific Reports. 10 (1): 18232. doi:10.1038/s41598-020-75406-w. ISSN 2045-2322. PMC 7588462. PMID 33106563.
  12. ↑ "ME/CFS Canadian Collaborative Team Conference" (PDF). Retrieved March 11, 2019.
  13. ↑ "UK CFS/ME Research Collaborative Conference programme" (PDF). Action for ME. Retrieved March 5, 2019.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

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