Capsaicin
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Capsaicin is the substance that makes chili peppers hot. It is often used externally for muscle and joint pain as well as peripheral neuropathy, either as a cream or as a trans-dermal patch. Eating capsaicin in chili peppers produces a euphoric in some people as a response to the heat.
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