Alcohol intolerance
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Alcohol intolerance may occur in ME/CFS. It usually develops after the onset of the illness, where the patient was previously able to tolerate alcohol. It forms part of a wider range of allergies and sensitivities that may develop during the course of the illness.
Prevalence[edit | edit source]
- 2001, In a Belgian study, 59.5% of patients meeting the Fukuda criteria and 63.7% of patients meeting the Holmes criteria, in a cohort of 2073 CFS patients, reported alcohol intolerance.[1]
- 1995, Katrina Berne, PhD, reported an estimated prevalence of 45-75% for alcohol intolerance (although she notes that this symptom may be underreported and therefore more prevalent than indicated).[2]
Symptom recognition[edit | edit source]
Notable studies[edit | edit source]
Possible causes[edit | edit source]
- Channelopathy has been proposed as a mechanism of the illness which would explain intolerance to alcohol and other drugs.[3]
- Gut fermentation problems[4]
- Alcohol is a depressant of the central nervous system, which tends to be hyper-reactive in people with ME/CFS[5]
- Alcohol is toxic for the liver, and many people with ME/CFS have suboptimal liver function[6]
- Alcohol can interfere with the methylation cycle[7]
- Alcohol is a vasodilator - this will exacerbate vascular symptoms such as neurally mediated hypotension or POTS[8]
Potential treatments[edit | edit source]
If a patient presents with alcohol intolerance, alcohol should be avoided, including that in mouthwashes and herbal tinctures.
Learn more[edit | edit source]
See also[edit | edit source]
References[edit | edit source]
- ↑ De Becker, P; McGregor, N; De Meirleir, K (September 2001), "A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome.", Journal of Internal Medicine, 250 (3): 234-240, PMID 11555128
- ↑ Berne, Katrina (December 1, 1995), Running on Empty: The Complete Guide to Chronic Fatigue Syndrome (CFIDS), 2nd ed., Hunter House, p. 58, ISBN 978-0897931915
- ↑ Verrillo - Channelopathies
- ↑ Verrillo - Gut fermentation and small intestine bacterial overgrowth (SIBO)
- ↑ Verrillo - Foods to Avoid
- ↑ Verrillo - Foods to Avoid
- ↑ Verrillo - Foods to Avoid
- ↑ Verrillo - Foods to Avoid