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A Regime for Antiretroviral Treatment of Myalgic Encephalomyelitis
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===Dosage details=== Our experience has shown that severely ill ME patients ([[Bell]] scale 0) can apparently start safely with an eighth of a [[Tenofovir]] tablet - in our case it was [[Viread]], which contains 245mg [[Tenofovir]] disoproxil per pill. Of course, I cannot guarantee whether this will apply to all patients; unfortunately, use of this drug is and for the time being remains an experiment that many do not want to forego, because they have their backs to the wall and are heading for a certain end without treatment. According to our findings, one can take a lot of time with the increase in dose and wait in peace until the organism has adapted to every further small increase. In our case, it took seven months to reach full dose. Patience is therefore required, because significant improvements only occur in most responders after reaching full dose. However, after three to four months of daily intake of 245mg, progress should become apparent. (There is, however, also talk of a patient who only experienced significant improvements after 6 months of Truvada application.) If it has not occurred by then, it can be assumed that the drug is not effective in a patient. The improvement in condition is incidentally often wave-like, with ups and downs, but the overall tendency should be an upwards one. Moderately and mildly ill patients can - according to the experiences of other patients described - presumably enter therapy at a higher dose with rapid increase or immediately at the full dose of 245mg. In that case, faster progress is to be expected if the drug is effective. But even in these patients, significant improvements are usually only to be expected after three to four months (cf. p. 3 here). The first small improvements are sometimes noticeable after a shorter period of time - in some patients also at low doses - but mostly concerning physiological processes, such as improved sleep quality and a return to an intact day/night rhythm, improved blood circulation in the limbs, fewer food intolerances, etc., but sometimes also concerning neurosensory symptoms, e.g. a reduction in sensory hypersensitivity.
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