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1970 London outbreak
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==Symptomatology== Symptomatology in order of prevalence was [[headache]], sore throat, [[nausea]], back pain, [[malaise]], vomiting, neck pains, tiredness, limb pains, [[depression]], dizziness, sore eyes, cough, coryza, chest pain, abdominal pain, photophobia, diarrhea, earache, laryngitis, paresthesia, faintness, jaw pain, bladder symptoms, [[Anorexia and eating disorders|anorexia]], [[Paresis|subjective limb weakness]], blurred vision, diplopia, and painful joints. A striking symptom reported was rapid fatigability with exercise and relapses over a prolonged period sometimes lasting several years. Duration of the illness varied greatly and was hard to determine because of relapses. Even those who recovered from the illness never fully regained their pre-illness level of health.<ref name="Dillon, 1978" /> Invasive testing was kept to a minimum so as to not create an atmosphere of anxiety in a vulnerable population. Serological tests were done for viruses, such as [[cytomegalovirus]], adenovirus, [[herpes simplex]], influenza A and B, parainfluenza 1 and 3, mumps, and [[Epstein-Barr virus]]; electron and immune electon microscopy; cell cultures were inoculated into lab animals; hematological, biochemical, bacteriological tests; cerebrospinal fluid examination; immunoglogulin, interferon, phyohemagglutin stimulation of peripheral lymphphocyctes, and lymphocyte cultures testing was done.<ref name="Dillon, 1974" /> Laboratory and other testing was unable to uncover an infectious agent, although the investigators believed the pattern of the outbreak pointed to an infective etiology.<ref name="Dillon, 1978" />
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